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    Glossary Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry

    advanced technique for separating and identifying compounds in samples

    Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry (UPLC-MS/MS) is an advanced analytical technique used to separate, identify, and quantify compounds in a sample. UPLC enhances the resolution and speed of liquid chromatography, while MS/MS provides highly sensitive and specific detection by breaking down molecules into fragments and analyzing their mass. This method is widely used in fields like pharmacology, biochemistry, and environmental science for precise and accurate analysis of complex mixtures.

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    1. Ultra-Performance Liquid Chromatography with Electrospray Ionization Tandem Mass Spectrometry for the Determination of Ketoconazole in Anti-Dandruff Shampoo Analytical Letters · 2014 · 1 citations
    2. Simultaneous determination of androgens and prostaglandins in human urine using ultra-high-performance liquid chromatography–tandem mass spectrometry Journal of Chromatography B · 2019 · 10 citations
    3. Determination of 13 janus kinase inhibitors in anti-alopecia cosmetics by ultra-high performance liquid chromatography-tandem triple quadrupole composite linear ion trap mass spectrometry Chinese Journal of Chromatography · 2025
    4. Simultaneous determination of androgens and prostaglandins in human urine using ultra-high-performance liquid chromatography–tandem mass spectrometry 2019
    5. Studies on the persistence of estradiol benzoate and nortestosterone decanoate in hair of cattle following treatment with growth promoters, determined by ultra-high-performance liquid chromatography–tandem mass spectrometry Journal of Chromatography A · 2009 · 18 citations
    6. Profiling steroid and thyroid hormones with hair analysis in a cohort of women aged 25 to 45 years old European journal of endocrinology · 2022 · 6 citations
    7. 1302 Disturbed sebum and microbiome composition in sensitive scalp Journal of Investigative Dermatology · 2018
    8. Development and validation of rapid and simultaneous method for determination of 12 hair-growth compounds in adulterated products by UHPLC–MS/MS Forensic Science International · 2018 · 4 citations
    9. Ex-vivo measurement of scalp follicular infundibulum delivery of zinc pyrithione and climbazole from an anti-dandruff shampoo Journal of pharmaceutical and biomedical analysis · 2017 · 12 citations
    10. Simultaneous determination of 30 hormones illegally added to anti-ageing functional foods using UPLC-MS/MS coupled with SPE clean-up Food Additives & Contaminants: Part A · 2014 · 6 citations
    11. A quantitative ultra-performance liquid chromatography high-resolution mass spectrometry analysis of steroids from human scalp hair Journal of pharmaceutical and biomedical analysis · 2022 · 7 citations
    12. Simultaneous Determination of Selected Steroids with Neuroactive Effects in Human Serum by Ultrahigh-Performance Liquid Chromatography–Tandem Mass Spectrometry ACS Chemical Neuroscience · 2024 · 5 citations
    13. An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of 5-alpha-dihydrotestosterone in human serum and plasma Clinical Chemistry and Laboratory Medicine (CCLM) · 2026
    14. An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of dehydroepiandrosterone sulfate in human serum and plasma Clinical Chemistry and Laboratory Medicine (CCLM) · 2025 · 1 citations
    15. Quantification of biotin in plasma samples by column switching liquid chromatography – tandem mass spectrometry Scandinavian journal of clinical and laboratory investigation · 2021
    16. Determination of 19 Steroid Hormones in Human Serum and Urine Using Liquid Chromatography-Tandem Mass Spectrometry Toxics · 2022 · 7 citations
    17. Establishing and Verifying a Robust Liquid Chromatography-Tandem Mass Spectrometry Method to Simultaneously Measure Seven Androgens Present in Plasma Samples Separations · 2022 · 3 citations
    18. Analytical method for the biomonitoring of bisphenols and parabens by liquid chromatography coupled to tandem mass spectrometry in human hair Ecotoxicology and Environmental Safety · 2022 · 12 citations
    19. Study on the Efficacy and Potential Mechanism of Topical Shen Bai Hair Growing Decoction against Androgenetic Alopecia Based on Ultrahigh Performance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry and RNA-seq ACS Omega · 2024
    20. Green and Emerging Microextraction Strategies for Bioanalytical Determination of Hormones: Trends, Challenges, and Applications Molecules · 2025
    21. MANAGEMENT OF ENDOCRINE DISEASE Hyperandrogenic states in women: pitfalls in laboratory diagnosis European Journal of Endocrinology · 2018 · 16 citations
    22. Long-term detection of methyltestosterone (ab-) use by a yeast transactivation system Archives of Toxicology · 2010 · 15 citations
    23. LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery Journal of Lipid Research · 2011 · 211 citations
    24. Design and Validation of a Sensitive Multisteroid LC-MS/MS Assay for the Routine Clinical Use: One-Step Sample Preparation with Phospholipid Removal and Comparison to Immunoassays International Journal of Molecular Sciences · 2022 · 9 citations
    25. Integrated chemometric fingerprints of antioxidant activities and HPLC–DAD–CL for assessing the quality of the processed roots of Polygonum multiflorum Thunb. (Heshouwu) Chinese Medicine · 2016 · 12 citations
    26. In-Depth Exploration of Chemical Constituents from Justicia procumbens L. Through UHPLC-Q-Exactive Orbitrap Mass Spectrometry Molecules · 2025
    27. Comprehensive HPLC and UPLC-MS/MS Analysis for the Multi-component Detection of Hair Growth Compounds in Consumer Health Products Chromatographia · 2026
    28. Endocrinology Clinical Chemistry and Laboratory Medicine · 2023
    29. Investigation by Imaging Mass Spectrometry of Biomarker Candidates for Aging in the Hair Cortex PloS one · 2011 · 21 citations
    30. (Un)targeted Scanning of Locks of Hair for Drugs of Abuse by Direct Analysis in Real Time–High-Resolution Mass Spectrometry Analytical Chemistry · 2016 · 34 citations