13 citations
,
July 2011 in “Journal of Dermatological Treatment” This study found that topical pimecrolimus is as effective as clobetasol propionate for treating alopecia areata, with better tolerability in terms of side effects.
12 citations
,
January 2022 in “International Journal of Clinical Practice” This study found that women with PCOS, especially those who are obese, showed higher oxidative stress and decreased antioxidant levels, correlating with metabolic syndrome and cardiovascular disease risk factors.
12 citations
,
January 2016 in “Journal of clinical biochemistry and nutrition” In this study, combining deferasirox with sorafenib significantly reduced liver fibrosis and preneoplastic lesions in rats while also lessening adverse effects compared to sorafenib alone.
11 citations
,
September 2013 in “Journal of The European Academy of Dermatology and Venereology” In this study, sensorineural hearing loss was significantly more frequent in patients with alopecia areata compared to healthy controls, suggesting a relationship between the autoimmune condition and hearing function.
9 citations
,
June 2024 in “Cell Reports” This study found that hair follicles play a significant role in regulating skin barrier function, with disruptions in the upper hair follicle affecting the epidermis, influencing processes like desquamation and sebum release, and leading to cell movement into the epidermis.
9 citations
,
August 2017 in “Journal of comparative pathology” This study suggests that uncontrolled embryonic trichogenesis may play a role in the development of trichoblastoma in rabbits.
8 citations
,
July 2018 in “European Journal of Dermatology” A medication may help with hair growth in psoriasis, and a skin condition might be linked to a specific bacteria.
8 citations
,
April 2011 in “Surgery today” This study found that sodium zinc dihydrolipoylhistidinate reduced chemotherapy-induced hair loss in rats, suggesting its potential as a treatment for this side effect.
7 citations
,
October 2022 in “Dermatology Practical & Conceptual” This study found that more than half of psoriasis patients used complementary and alternative medicine without informing their physicians, highlighting a need for increased awareness among dermatologists.
7 citations
,
May 2007 in “PubMed” This study found that women with androgenetic alopecia were more insulin resistant than healthy controls, suggesting the use of beta cell function and insulin sensitivity indices to measure insulin resistance in this population.
7 citations
,
March 2007 in “International Journal of Dermatology” This study observed that antisense oligonucleotides targeting FGFR-1 increased cellular activity in hair follicle cultures from mice, suggesting potential clinical utility for treating baldness.
6 citations
,
March 2018 in “Journal of Medicinal Food” This study demonstrated that water-soluble peptides from egg yolk, termed "hair growth peptide," stimulated human hair follicle cell growth and improved hair growth in female pattern hair loss.
6 citations
,
February 2002 In this study, the bark of Spondias mombin showed potential anti-tumor effects in rats with induced cancer, reducing symptoms like hair loss and low food intake, but tachycardia was noted as a possible side effect.
6 citations
,
January 1994 in “Skin Pharmacology and Physiology” This study suggests that the attachment and interaction between dermal papillae and the hair bulb matrix are crucial for normal hair follicle growth and development in vitro.
5 citations
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May 2022 in “Biomedicines” This study found that the green alga Botryococcus terribilis and its novel compounds significantly promoted hair growth marker gene expression in hair follicle dermal papilla cells without cytotoxic effects.
5 citations
,
June 2017 in “in Vivo” This study found that vitamin C deficiency in SMP-30/GNL-KO mice affected gene expression related to hair growth and cell growth, resulting in delayed hair growth compared to those with adequate vitamin C.
5 citations
,
February 2015 in “Endocrinology Diabetes and Metabolism Case Reports” This case report describes a patient with autoimmune polyglandular syndrome type 3 who experienced total hair regrowth following the successful control of diabetes with insulin therapy.
5 citations
,
January 2012 in “Biological & Pharmaceutical Bulletin” This study found that extract of Hura crepitans inhibited androgen-accelerated NT-4 activity and ameliorated the retardation of hair regrowth in dihydrotestosterone-implanted mice, suggesting a potential role for NT-4 inhibitors in AGA.
4 citations
,
January 2023 in “Journal of Clinical Investigation” This study identified a recurrent mutation in the endothelin receptor type A associated with mandibulofacial dysostosis with alopecia, and proposed a mechanism involving increased ligand affinity due to structural changes.
4 citations
,
January 2017 in “Journal of veterinary medical science” This report diagnosed a mass below a dog's eye as desmoplastic tricholemmoma based on histopathological and immunohistochemical findings.
3 citations
,
September 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that enhanced wound healing in oral mucosa involves a SOX2-regulated transcriptional network which includes increased expression of keratin K75, and interaction of K75 with the LINC complex may play a crucial role in promoting rapid wound repair.
3 citations
,
December 2017 in “Clinical and Experimental Dermatology” In this case study, researchers observed reversible scalp hair loss associated with centrifugal lipodystrophy, potentially linked to altered leptin expression in inflamed adipose tissue.
3 citations
,
January 1998 in “ACTA HISTOCHEMICA ET CYTOCHEMICA” This study used rapid-freezing immunocytochemistry to successfully map the ultrastructural localization of hair keratins in human scalp hair, primarily finding them in macrofibrils in the cortex and endocuticle.
3 citations
,
January 1989 in “Journal of Japan Oil Chemists Society” This study examined the effects of six surfactants on hair and scalp, finding varying irritation levels and impacts on protein denaturation and scalp turnover time, with AMT suggested as a good detergent.
2 citations
,
October 2022 in “Jikken Dobutsu” This study found that Philippines stingless bee propolis extract promotes hair growth in mice by activating the Wnt/β-catenin signaling pathway and stimulating hair follicle development.
2 citations
,
October 2020 in “Research Journal of Health Sciences” This study documented that discoid lupus erythematosus was the most common cause of alopecia among patients at a dermatology outpatient clinic in Nigeria from 2014 to 2019.
2 citations
,
March 2015 in “Human & Experimental Toxicology” This study found that hyperbaric oxygen treatment in rats led to structural changes in epidermis and dermis, including decreased E-cadherin expression and increased connective tissue.
2 citations
,
January 2014 in “Turkish Journal of Medical Sciences” This study found that the TrichoScan software effectively differentiated between androgenetic alopecia and telogen effluvium in women with diffuse hair loss, aligning with clinical diagnoses.
2 citations
,
July 2011 in “International Journal of Dermatology” This case report describes three instances of eosinophilic pustular folliculitis lacking visible pustules, which histopathology confirmed involve eosinophilic infiltration around hair follicles.
2 citations
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January 1994 in “Nihon Chikusan Gakkaiho” In this research, Holstein cows immunized with human hair keratin produced antibodies in both colostrum and regular milk that specifically bind to hair keratin, enhancing hair tensile strength without affecting skin keratin.