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Hair proteins have weak spots in their α-helical segments.

Type I interferons play a key role in the development of various skin diseases.

Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.

FOL-005, a hair growth promoter, acts locally on mouse skin where injected and could be a promising hair loss treatment.

Two microRNAs affect hair follicle development in sheep by targeting specific genes.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

A certain genetic variation in the IL1A gene may lower the risk of a hair loss condition in Chinese people.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.

Quercetin may help with PCOS symptoms, but more research is needed.

Researchers found new genes involved in hair growth, which could help develop new hair treatments.

Ruxolitinib may help treat hair loss by reducing inflammation, promoting hair growth signals, and protecting hair follicle immunity.

Glutamic acid helps increase hair growth in mice.

A new gene mutation causes insulin resistance in a girl and her mother.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

The research found that a complex gene network, controlled by microRNAs, is important for hair growth in cashmere goats.

The combined treatment with engineered bacteria and yellow LED light improved wound healing in mice.

Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.