research Genome-Wide Association Study of Skin Complex Diseases
Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.
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research Host Genetic Susceptibility and Impacts of Dietary Factors on COVID-19
Certain genes and nutrients like vitamin D, zinc, and omega fatty acids affect COVID-19 severity and infection risk.
research Genome-Wide Association Studies for Immunoglobulin Concentrations in Colostrum and Serum in Chinese Holstein
Certain genes influence immunoglobulin levels in Chinese Holstein cows, which can improve calf health.
research The Immune Response to COVID-19: Does Sex Matter?
Men and women get COVID-19 at similar rates, but men tend to get sicker and have a higher risk of dying, while women usually have stronger immune responses and vaccine reactions.
research Antroquinonol Exerts Immunosuppressive Effect on CD8+ T Cell Proliferation and Activation to Resist Depigmentation Induced by H2O2
Antroquinonol may help prevent skin depigmentation by suppressing certain immune cells.
research Quiescent Tissue Stem Cells Evade Immune Surveillance
Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.
research Evaluation of the Relationship Between Alopecia Areata and Viral Antigen Exposure
Hepatitis B virus exposure may be linked to increased risk of alopecia areata.
research Suppression of Cutibacterium Acnes-Mediated Inflammatory Reactions by Fibroblast Growth Factor 21 in Skin
FGF21 can help reduce skin inflammation caused by C. acnes.
research Fibroblasts: Immunomodulatory Factors in Refractory Diabetic Wound Healing
Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.
research Immuno-Endocrinology of COVID-19: The Key Role of Sex Hormones
Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.
research Toll-Like Receptor 4 (TLR4): New Insights into Immunity and Aging
TLR4 is important in aging-related diseases and could be a new treatment target.
research Defining the Short-Term and Long-Term Skin Manifestations of COVID-19: Insights After More Than Three Years of the Pandemic
COVID-19 can cause various skin issues, but long-term skin problems are rare.
research Hypothesis: Wound-Induced TLR3 Activation Stimulates Endogenous Retinoic Acid Synthesis and Signalling During Regeneration
Activating TLR3 may help produce retinoic acid, important for tissue regeneration.
research Primary Cicatricial Alopecias
The document concludes that early diagnosis and treatment are crucial for managing rare hair loss disorders and that more research is needed to improve treatment strategies.
research JAK Inhibitors: New Players in the Field of Immune-Mediated Diseases Beyond Rheumatoid Arthritis
JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.
research Autoimmunity and Autoimmune Co-Morbidities in Psoriasis
Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.
research Aberrant Inflammasome Activation as a Driving Force of Human Autoimmune Skin Disease
Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.
research Cutaneous Lupus Erythematosus: Overview and Treatment
The document concludes that Cutaneous Lupus Erythematosus has different forms, is influenced by genetic and environmental factors, and can be treated with various medications, but more targeted therapies are needed.
research Therapeutic Potential of Patient iPSC-Derived Melanocytes in Autologous Transplantation
Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
research The Promise and Challenges of Cell Therapy for Psoriasis
Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
research GPX4 mRNA Levels in Polymorphonuclear Neutrophils Are Negatively Correlated with Autoantibody Production, Disease Activity, and Lupus Alopecia in Systemic Lupus Erythematosus
Lower GPX4 mRNA levels are linked to higher disease activity and symptoms in lupus patients.
research Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
research What Causes Hidradenitis Suppurativa?—15 Years After
Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.
research XEDAR Activates the Non-Canonical NF-κB Pathway
XEDAR triggers a specific signaling pathway in cells.
research Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity
Chicken feather gene mutation helps understand human hair disorders.
research Biology of Melanocytes in Mammals
Melanocytes are important for skin and hair color and protect the skin from UV damage.
research Immune-Mediated Skin Reactions Induced by Recombinant Antibodies and Other TNF-Alpha Inhibitors
TNF-alpha inhibitors can cause various immune-related skin issues.
research Cicatricial Alopecia: Early Diagnosis and Treatment Strategies
Early diagnosis and aggressive treatment are crucial for Cicatricial Alopecia, and treatment effectiveness varies among patients.
research Measurement of Level of Vitamin D and Antioxidants in Discoid Lupus Erythematosus Patients
Patients with Discoid Lupus Erythematosus have lower vitamin D and antioxidant levels and higher oxidative stress.
research Physiological Functions of PP2A: Lessons from Genetically Modified Mice
Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.