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Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

5α-reductase inhibitors like finasteride and dutasteride can help treat skin disorders stimulated by androgens, such as hair loss and acne.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Finasteride effectively treats male pattern hair loss with a 1 mg daily dose.

Finasteride effectively treats male hair loss, improving growth and density.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Gene differences may affect baldness treatment response in Korean men.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Minoxidil may help treat hair loss by reducing the activity of a specific enzyme linked to baldness.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

Finasteride effectively reduces hair loss by decreasing androgen levels.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Preventing hair loss is more effective than regrowth; oral finasteride is a realistic option.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.

A new plant extract from Avicennia marina could potentially be used to treat common hair loss.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.