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Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.

Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.

Immune cells are essential for early hair and skin development and healing.

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

Larger ovarian size is linked to higher insulin resistance in women with PCOS.

People with PCOS have higher levels of PAI-1, which may increase their risk of heart disease and fertility issues.

The new rodent model successfully mimics non-lean human PCOS symptoms.

Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.

Many women experience sexual dysfunction, but few seek help, and better treatment and medical training are needed.

Mice with a changed Hr gene lose and regrow hair due to changes in the gene's activity.

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.

Kelulut Honey can help regulate sex hormone receptors in rats with Polycystic Ovary Syndrome, similar to common medications.

Proxalutamide improved recovery, lowered death rates, and reduced hospital stay for COVID-19 patients.

Spironolactone treatment increases the amount of testosterone available in the body.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Finasteride and metformin both help treat PCOS, but using them together works best.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Neurosteroids show promise for treating epilepsy and more research is needed.

The conclusion is that androgen receptor gene polymorphism might be a marker for polycystic ovary syndrome, but more research is needed.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.