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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

About 6.5% of young Caucasian women in Spain have polycystic ovary syndrome.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Growing human skin cells in a 3D environment can stimulate new hair growth.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Human skin can make serotonin and melatonin.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Nerves are crucial for the regeneration of various body parts in many animals.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Noggin is necessary to start the hair growth phase in skin after birth.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

PGD2 stops hair growth and is higher in bald men with AGA.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Hair loss common in Australia; men affected earlier, more often than Asians; women less concerned.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.