research Conditional Activin Receptor Type 1B (Acvr1b) Knockout Mice Reveal Hair Loss Abnormality
Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
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research The Management of EGFR Inhibitor Adverse Events: A Case Series and Treatment Paradigm
Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.
research Characteristics of Non-Melanoma Skin Cancers of the Cutaneous Perioral and Vermilion Lip Treated by Mohs Micrographic Surgery
Mohs micrographic surgery is effective for early-stage non-melanoma skin cancers on the lips, with basal cell carcinoma more common on the upper cutaneous lip and squamous cell carcinoma more common on the lower vermilion lip.
research Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models
Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.
research Management of Toxicities of Targeted Therapies
Targeted therapies for lung cancer are effective but require careful management of side effects to benefit patients.
research ESGCT and FSGT Collaborative Congress Helsinki, Finland September 17–20, 2015 Abstracts
The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
research 3D Analysis of Facial Morphology in Dutch Children with Cancer
Children with cancer had slightly more unusual facial shapes than healthy kids, but not enough to easily tell them apart.
research The PDGF/PDGFR Pathway as a Drug Target
The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
research Extraskeletal Actions of Vitamin D
Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.
research Circadian Clock-Mediated Control of Stem Cell Division and Differentiation: Beyond Night and Day
The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.
research VP-16-213 (Etoposide): The Mandrake Root from Issyk-Kul
Etoposide is effective in treating several cancers, especially small cell lung cancer, with acceptable side effects.
research Presentation, Impact and Prevention of Chemotherapy-Induced Hair Loss: Scalp Cooling Potentials and Limitations
Scalp cooling can reduce chemotherapy-induced hair loss and should be available in all hospitals.
research BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor Under Steady-State Conditions
BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
research Gefitinib: An Adverse Effects Profile
Gefitinib can cause skin problems, diarrhea, and nausea, but rarely causes severe lung disease or hair loss.
research Polycystic Ovary Syndrome and Its Differential Diagnosis
The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.
research Ephrins Negatively Regulate Cell Proliferation in the Epidermis and Hair Follicle
Ephrins slow down skin and hair follicle cell growth.
research Premature Adrenarche: Early Maturation of Adrenal Glands in Children
Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.
research Protection Against Chemotherapy-Induced Alopecia: Targeting ATP-Binding Cassette Transporters in the Hair Follicle
Increasing ABC transporters in hair follicles may prevent chemotherapy-induced hair loss.
research Adam10 Haploinsufficiency Causes Freckle-Like Macules in Hairless Mice
A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
research Acutely Ill Patients in Internal Medicine Departments Want Treatment for Undiagnosed, Symptomatic Skin Conditions
Most hospitalized internal medicine patients have undiagnosed skin problems and want them treated.
research Dermatologic Diseases in Ferrets: Comprehensive Review and Treatment
The document concludes that early diagnosis and treatment are crucial for managing skin diseases in ferrets.
research Perspectives in Head and Neck Medical Oncology
The document concludes that systemic therapy is becoming more important in treating head and neck cancer, with new treatments showing promise.
research An Industry Update: What's New in the Field of Therapeutic Delivery This Month?
New drugs for Alzheimer's and rheumatoid arthritis advanced, a Zika vaccine is in development, and there were business deals in anesthesia and oncology.
research BMI1 Is Required for Melanocyte Stem Cell Maintenance and Hair Pigmentation
BMI1 is essential for preventing hair greying and maintaining hair color.
research Epigenetics of Colorectal Cancer
Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
research Capture of Endothelial Cells Under Flow Using Immobilized Vascular Endothelial Growth Factor
A surface with VEGF can specifically capture endothelial cells from flowing fluids.
research The Evolutionary Impact of Androgen Levels on Prostate Cancer in a Multi-Scale Mathematical Model
Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
research Skin Cancer: Understanding the Transformation from Conventional to Advanced Treatment Approaches
New treatments like nanotechnology show promise in improving skin cancer therapy.
research Deletion of the MAD2L1 Spindle Assembly Checkpoint Gene Is Tolerated in Mouse Models of Acute T-Cell Lymphoma and Hepatocellular Carcinoma
Deleting the MAD2L1 gene is tolerated in certain mouse cancer models.
research A Novel Connexin 26 Mutation in a Patient Diagnosed with Keratitis–Ichthyosis–Deafness Syndrome
A new mutation in the Connexin 26 gene was found in a patient with KID syndrome, expanding the known disorders linked to this gene.