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Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Finasteride temporarily lowers male rat fertility without affecting libido.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

A new method accurately measures nine specific hormones in human blood.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

A mouse gene mutation increases the risk of skin cancer.

The document concludes that new methods improve the accuracy of diagnosing scalp alopecia and challenges the old way of classifying it.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

A combination of nanomilled oral testosterone and dutasteride normalized testosterone levels in men with low testosterone and is safe for short-term use.

Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.

Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

The boy's itchy scalp and hair loss were likely due to head lice treatment.

Testosterone therapy increases bone density in older men with low testosterone levels.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Finasteride safely lowers DHT levels without affecting testosterone.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

DHT, a testosterone byproduct, causes male pattern baldness.

Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.

Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.

High doses of finasteride cause cell growth and tumors in mice.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.