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This study found that knock-down of keratin 15 in various cell lines affected cell spreading, morphology, migration, differentiation, and proliferation, suggesting its role in maintaining the stem cell nature of keratinocytes.

This study observed that stem cells from the hair follicle dermis share similarities with bone marrow-derived mesenchymal stem cells and have potential to form neural-like cells under specific conditions.

This study found that using trypsin digestion to extract keratinocytes from the hair follicle bulge results in a higher yield and faster growth of stem keratinocytes compared to the explant method.

In this study, using tyrosine as a cross-linking agent for hair perming showed better initial results compared to commercial products, though efficiency decreased after washing without compromising hair strength.

This study found that adapalene-loaded solid lipid microparticles may enhance targeted drug delivery into sebum due to their similarity to sebum components, although both this formulation and a standard cream showed equivalent follicular penetration.

In this study, researchers developed a simplified and reliable method to prepare human hair shaft samples, achieving over 75% protein extraction efficiency and improved keratin sequence coverage, with the approach showing high reproducibility across different labs and operators.

This study developed a rapid method to extract proteins from human hair, revealing phosphorylation on serine and threonine residues in alpha-keratins and matrix proteins.

This study reported detailed three-dimensional ultrastructural observations of human hair and hair follicles using a modified preparation method, including morphological differences in hair bulb cell layers and surface projections on root sheath cells.

This study explored using tyrosine as a cross-linking agent for curling Asian hair and found that it could shape hair effectively before washing without damaging the fibers, though the method was less effective after washing compared to commercial products.

In this study, proteolytic enzymes applied to mice skin caused severe degeneration in hair follicles, including detachment of stem cells from their niche, suggesting potential impairment of stem cell function.

This study purified a transglutaminase enzyme from human epidermis that requires calcium or strontium for activity and forms cross-linked polymers, but its detailed activation mechanism remains unclear.

This study found that adding iontophoresis of papain and chymotrypsin to laser treatment significantly increased hair reduction in women with facial hirsutism compared to laser treatment alone over six months.

This study showed that keratinase pretreatment effectively reduces the time for enzymatic unhairing in bovine hides by opening channels for faster penetration, which shortens the process by over 50% and enhances leather quality.

The researchers reported that applying proteolytic enzymes to mice skin negatively affected hair follicles, leading to degeneration and potential impairment of stem cells from the bulge area.

This study developed a new STR typing strategy for forensic casework, enabling the simultaneous analysis of 11 polymorphic systems, particularly useful for limited or degraded DNA samples such as telogen hair roots.

In this study, researchers identified a highly reactive, isozyme-specific sequence for TGase 3, contributing to understanding its distinct functional role and activity distribution in the mouse epidermis.

This study found that combining Alexandrite laser with iontophoresis of chymotrypsin and papain enzymes reduced the laser pulse requirements compared to laser alone for treating paradoxical hypertrichosis in women with facial hirsutism, suggesting potential clinical benefits in managing this condition.

This study explored the potential of using isoenzyme detection after electrophoresis to characterize human hair, though no new clinical results are reported.

This study found that optimizing proteomic genotyping conditions from single human hair samples significantly improves the detection of genetically variant peptides, enhancing human identification with high precision across different biogeographic backgrounds.

This study found that an enzymatic method effectively identified chemical treatments like perming and dyeing by detecting higher degradation in treated hair compared to untreated hair.

This study found that enzyme depilation of lambskins can cause damage due to the removal of collagen VI, suggesting the need for a protease that avoids this interaction for successful application.

This study purified trichohyalin protein from pig tongue epithelium, characterizing its unique properties and structure, which may facilitate future functional research.

This study found that aged tritiated thymidine breaks down and incorporates into cytoplasmic macromolecules, not DNA, suggesting caution in its use.

This study suggests that trichohyalin is modified by peptidyl-arginine deiminase before being cross-linked by TGase 3, allowing the formation of rigid structures in hair follicle cells.

This study focuses on improving the detection and characterization of an enzyme in guinea pig hair follicles that converts arginine to citrulline, highlighting challenges with assay sensitivity and reproducibility.

This study introduced a method to isolate and separate microfibrillar proteins from human hair, identifying previously undetected glycine- and tyrosine-rich proteins.

Transamidases are present in the epidermis but their exact role is unclear.

In this study, researchers used in silico mutagenesis to identify key calcium-binding sites influencing the stability of Rand protease from Bacillus subtilis, potentially enhancing its application in industries like leather dehairing by improving stability and eliminating the need for additional metal ions during the process.