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The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Human skin can make serotonin and melatonin, which help protect and maintain it.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Growing human skin cells in a 3D environment can stimulate new hair growth.

Human skin can make serotonin and melatonin.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Lactate production is important for activating hair growth stem cells.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

Mannosylerythritol lipids are good for skin and hair care products.

Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.

Skin has specialized touch receptors that can tell different sensations apart.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Muscles and nerves that cause goosebumps also help control hair growth.