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The NUDT15 gene variant causes severe side effects from azathioprine in some Indian patients.

The ketogenic diet can worsen biotin deficiency, suggesting a need for biotin supplements.

Eclipta alba extract may work as an anticancer agent and help reverse drug resistance.

Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.

Dosing time affects finasteride's effectiveness and safety in rats.

A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.

New treatments for diabetes, central nervous system repair, and cartilage injury were found, and a way to create functional hair follicles from stem cells was developed.

Hair growth genes work better with more glucose due to changes in gene-regulating markers.

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.

PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.

Topical 5-Fluorouracil can rarely cause nerve damage, especially in people with a certain genetic deficiency.

Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.

Stopping minoxidil and draining fluid around the heart can save lives in rare cases.

Dogs with dermatomyositis, especially Collies and Shetland Sheepdogs, need better treatments for their skin and muscle inflammation.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

Patients with RASopathies have a higher risk of autoimmune disorders and should be routinely screened.

L-(+)-Tartaric Acid may help increase certain hair growth genes without harming cells.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Glycogen metabolism is important for energy and processes in human hair follicles, and hair follicles may produce glucose from lactate.

Hair follicle stem cells can change their role to ensure proper hair development.

Stabilizing HIF1A in hair follicles increases glycolysis, which may help reduce oxidative stress and support hair growth.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Zinc deficiency disrupts hair growth and cycle, but zinc supplements can fix this.

The document summarizes medical findings on topics like heart rhythm treatment, sleep apnea therapy, and various health conditions and treatments.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.