Search
for

    Glossary Translocator Protein

    protein on mitochondria involved in cholesterol transport and stress response

    The Translocator Protein (TSPO), formerly known as the Peripheral Benzodiazepine Receptor (PBR), is a protein found on the outer membrane of mitochondria, the energy-producing structures in cells. It plays a crucial role in transporting cholesterol into mitochondria, which is essential for the production of steroid hormones. TSPO is also involved in cellular stress responses and inflammation, making it a target for research in various medical fields, including neurology and oncology.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Antidepressant-like effect of fluoxetine may depend on translocator protein activity and pretest session duration in forced swimming test in mice Behavioural Pharmacology · 2017 · 7 citations
    2. Cytoprotective effects of paeoniflorin are associated with translocator protein 18 kDa Biomedicine & pharmacotherapy · 2018 · 3 citations
    3. Ornithine Decarboxylase Expression Leads to Translocation and Activation of Protein Kinase CK2 in Vivo Journal of Biological Chemistry · 1997 · 52 citations
    4. Overexpression of the 18 kDa translocator protein (TSPO) in the hippocampal dentate gyrus produced anxiolytic and antidepressant-like behavioural effects Neuropharmacology · 2017 · 25 citations
    5. Cyclosporin A Promotes Hair Epithelial Cell Proliferation and Modulates Protein Kinase C Expression and Translocation in Hair Epithelial Cells Journal of Investigative Dermatology · 2001 · 45 citations
    6. Midazolam Ameliorates the Behavior Deficits of a Rat Posttraumatic Stress Disorder Model through Dual 18 kDa Translocator Protein and Central Benzodiazepine Receptor and Neurosteroidogenesis PLoS ONE · 2014 · 56 citations
    7. Human Hairless Protein Roles in Skin/Hair and Emerging Connections to Brain and Other Cancers Journal of Cellular Biochemistry · 2017 · 15 citations
    8. Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research Journal of Neuroendocrinology · 2015 · 123 citations
    9. Role of neurosteroids in the anticonvulsant activity of midazolam British Journal of Pharmacology · 2011 · 28 citations
    10. Over-expression of TSPO in the hippocampal CA1 area alleviates cognitive dysfunction caused by lipopolysaccharide in mice Brain Research · 2016 · 18 citations
    11. TSPO activation modulates the effects of high pressure in a rat ex vivo glaucoma model Neuropharmacology · 2016 · 16 citations
    12. Benzothiazepines, diltiazem and JTV-519, exert an anxiolytic-like effect via neurosteroid biosynthesis in mice Journal of Pharmacological Sciences · 2020 · 1 citations
    13. Mackerel-Derived Fermented Fish Oil Promotes Hair Growth by Anagen-Stimulating Pathways International Journal of Molecular Sciences · 2018 · 14 citations
    14. Characterization of Mouse Profilaggrin: Evidence for Nuclear Engulfment and Translocation of the Profilaggrin B-Domain during Epidermal Differentiation 2002 · 25 citations
    15. Androgen Receptors and Androgen-Dependent Initiation of Protein Synthesis in the Prostate Vitamins and hormones · 1976 · 59 citations
    16. Procyanidin B-2, extracted from apples, promotes hair growth: a laboratory study 2002 · 37 citations
    17. Secreted Frizzled-related protein 4 inhibits the regeneration of hair follicles PeerJ · 2019 · 7 citations
    18. 4-<i>O</i>-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β Signaling Biomolecules & Therapeutics · 2017 · 5 citations
    19. Caspase-3 Regulates YAP-Dependent Cell Proliferation and Organ Size Molecular Cell · 2018 · 90 citations
    20. Effects of dihydrotestosterone on rat dermal papilla cells in vitro European Journal of Pharmacology · 2015 · 19 citations
    21. Hair growth–promoting effects of Enz_MoriL on human dermal papilla cells through modulation of the Wnt/β-Catenin and JAK-STAT signaling pathways Archives of dermatological research · 2024
    22. 592 Cross-interactions of BMP and WNT signaling pathways attenuate androgen effect on HFSC differentiation Journal of Investigative Dermatology · 2019
    23. A new way to restore tumour suppressor function Nature Reviews Drug Discovery · 2013
    24. K15 & Id3 expression in intact and regenerating adult vibrissae rodent hair follicles 2009
    25. Introduction: splintering urbanism Edward Elgar eBooks · 2007
    26. Targeting receptor–regulator interactions Nature Reviews Drug Discovery · 2013
    27. The reduction of selenium(IV) by boreal Pseudomonas sp. strain T5-6-I – Effects on selenium(IV) uptake in Brassica oleracea Environmental research · 2019 · 22 citations
    28. Chaperones as thermodynamic sensors Nature Reviews Drug Discovery · 2013
    29. Meloside A Protects Dermal Papilla Cells from DHT-Induced Damage via Androgen Receptor Modulation Current Issues in Molecular Biology · 2025
    30. Evidence for Novel Functions of the Keratin Tail Emerging from a Mutation Causing Ichthyosis Hystrix Journal of Investigative Dermatology · 2001 · 130 citations