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    Did you mean Transgenic Mouse Model?
    Glossary Transgenic Mouse Model

    A transgenic mouse model is a genetically modified organism that has had a foreign gene inserted into its genome, allowing researchers to study the effects of specific genes on biological processes, including hair loss and hair biology. These models are particularly relevant in the field of hair research as they can mimic human hair loss conditions, such as androgenetic alopecia or alopecia areata, providing insights into the underlying mechanisms and potential therapeutic targets. Key distinguishing characteristics of transgenic mouse models include the ability to control gene expression and the capacity to observe phenotypic changes in hair growth and follicle development in a living organism.

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    1. Transgenic mouse models support HCR as an effector gene in the PSORS1 locus 2004 · 37 citations
    2. Characterization of a new, inducible transgenic mouse model with GFP expression in melanocytes and their precursors Gene Expression Patterns · 2017 · 14 citations
    3. A transgenic mouse model to study the role of epidermal growth factor (EGF) in hair and skin development 2002
    4. TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia Cell Death and Disease · 2016 · 38 citations
    5. Transgenic rescue of desmoglein 3 null mice with desmoglein 1 to develop a syngeneic mouse model for pemphigus vulgaris Journal of Dermatological Science · 2011 · 17 citations
    6. HPV8 Field Cancerization in a Transgenic Mouse Model Is due to Lrig1+ Keratinocyte Stem Cell Expansion Journal of Investigative Dermatology · 2017 · 25 citations
    7. Characterization of Transgenic NSG-SGM3 Mouse Model of Precision Radiation-Induced Chronic Hyposalivation Radiation Research · 2022 · 5 citations
    8. G4, is a new transgenic mouse model for the polycystic ovaries syndrome 2019
    9. Dormant tumor cells in ret transgenic mouse melanoma model and their interaction with memory T cells heiDOK (Heidelberg University) · 2012
    10. A Mouse Model of Androgenetic Alopecia Endocrinology · 2010 · 42 citations
    11. Is the “Comb Over” Dying? A Mouse Model for Male Pattern Baldness (Androgenic Alopecia) Endocrinology · 2010 · 3 citations
    12. Ornithine decarboxylase transgenic mice as a model for human atrichia with papular lesions Experimental dermatology · 2000 · 20 citations
    13. Transgenic Flash Mice for In Vivo Quantitative Monitoring of Canonical Wnt Signaling to Track Hair Follicle Cycle Dynamics Journal of Investigative Dermatology · 2014 · 16 citations
    14. Transgenic HPV11-E2 protein modulates URR activity in vivo Transgenic Research · 2023 · 2 citations
    15. Animal Models of Psoriasis – What Can We Learn from Them? Journal of Investigative Dermatology · 1999 · 127 citations
    16. Alopecia areata − animal models Clinical and Experimental Dermatology · 2002 · 69 citations
    17. Directed Expression of Keratin 16 to the Progenitor Basal Cells of Transgenic Mouse Skin Delays Skin Maturation The Journal of Cell Biology · 1998 · 79 citations
    18. Evaluation of Animal Models Suitable for Hair Research and Regeneration InTech eBooks · 2018 · 3 citations
    19. Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound Healing PLOS ONE · 2012 · 23 citations
    20. Generating mouse models of degenerative diseases using Cre/lox-mediated in vivo mosaic cell ablation Journal of Clinical Investigation · 2011 · 20 citations
    21. Two novel CreER<sup>T2</sup> transgenic mouse lines to study melanocytic cells in vivo Pigment Cell & Melanoma Research · 2022 · 1 citations
    22. K6/ODC transgenic mice as a sensitive model for carcinogen identification Toxicology Letters · 2000 · 57 citations
    23. High‐Sulfur Protein Gene Expression in a Transgenic Mouse Annals of the New York Academy of Sciences · 1991 · 10 citations
    24. The human keratins: biology and pathology Histochemistry and Cell Biology · 2008 · 1398 citations
    25. GROWTH FACTORS IN HAIR ORGAN DEVELOPMENT AND THE HAIR GROWTH CYCLE Dermatologic Clinics · 1996 · 90 citations
    26. The impact of VDR expression and regulation in vivo 2017 · 25 citations
    27. hKAP1.6 and hKAP1.7, Two Novel Human High Sulfur Keratin-Associated Proteins are Expressed in the Hair Follicle Cortex 2002 · 24 citations
    28. A Niche Above: A Novel Modality of Stem Cell Regulation in Mammalian Skin Epidermis Cell stem cell · 2021
    29. Visualising Androgen Receptor Activity in Male and Female Mice PloS one · 2013 · 89 citations
    30. Conditional telomerase induction causes proliferation of hair follicle stem cells Nature · 2005 · 414 citations