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This study found that nonionic liposomes were the most effective vehicle for delivering reporter genes into the skin of rat pups, compared to other liposome and nonliposome formulations.

This review discusses the development and application of multiphoton microscopy in dermatology, highlighting its advantages and potential future research directions without reporting new clinical results.

This review highlights the potential of permeation enhancers to improve the delivery of active ingredients across the skin, optimizing therapeutic outcomes despite challenges posed by individual variability and environmental factors, according to the authors' analysis of current understanding and applications in skincare and transdermal therapies.

This study found that electroosmotic flow through hair follicles significantly contributes to solution flow during iontophoresis in hairless mouse skin.

This review discusses transdermal drug delivery using hydrogel-forming microneedles and highlights their potential for disease treatment, but notes challenges in their clinical application.

This review summarizes the use of 3D printing technologies for creating microneedles and evaluates their associated benefits, challenges, and regulatory considerations, but does not present new experimental results.

The researchers developed semi-dissolving microneedle patches using TEMPO-oxidized bacterial cellulose nanofibers, which allow effective transdermal drug delivery by forming micro-channels for large drug quantities, overcoming traditional microneedles' low drug loading.

In this study, a new formulation of all-trans retinoic acid bound to polyvinyl alcohol showed reduced skin inflammation and sustained drug release for up to six days compared to free ATRA in vitro and in vivo.

This study found that combining fractional erbium-glass laser therapy with topical minoxidil significantly improved hair density and diameter in men with androgenetic alopecia compared to using minoxidil alone over a 24-week period, with no serious adverse events reported.

This review discusses the challenges of traditional phytochemical delivery methods and highlights the potential of microneedles to improve intra/transdermal delivery, reporting no new clinical results.

This study found that nanostructured lipid carriers provided better skin-targeted delivery and drug loading for lidocaine than nanoethosomes, indicating improved local anesthetic efficacy in vitro.

This study found that elastic liposomes enhanced skin delivery of genistein in haired skin compared to conventional liposomes, but showed decreased effectiveness in hairless skin.

This review discusses transdermal drug delivery using hydrogel-forming microneedles and highlights their potential and challenges for clinical application, but it reports no new clinical findings.

This study found that applying benzyl nicotinate on open hair follicles led to a significant increase in blood flow, highlighting the role of the follicular pathway in epidermal penetration.

This study found that ketorolac tert-butyl ester enhances skin permeation and follicular absorption compared to ketorolac, highlighting the role of lipophilicity and solubility in prodrug design.

This review discusses various patent articles on microemulsion carriers in drug delivery systems and reports no new empirical findings.

This study found that using short durations of heat with chemical penetration enhancers improved isotretinoin delivery to human skin, especially via the hair follicles.

This study found that a dissolvable microneedle device delivering rapamycin and epigallocatechin gallate nanoparticles significantly enhanced hair regrowth in C57BL/6 mice within 7 days, demonstrating increased hair shaft growth and follicle density with minimal inflammation compared to untreated mice.

This study found that retinoic acid pre-treatment enhanced the efficiency of gene transfer into mouse skin for potential therapeutic applications.

This review discusses the potential use of spin traps in cosmetic products to limit reactive oxygen species generated by pollution, emphasizing the need for further research due to toxicity and regulatory concerns.

This paper reviews the development of transdermal drug delivery systems for skin diseases, from first to fourth generation, and highlights ongoing challenges and the importance of clinical trials, but provides no new clinical results.

This study found that newly developed nanogels for transdermal delivery of finasteride were stable, showed excellent drug permeation through the skin, and ensured biocompatibility without causing irritation or toxicity.

In this study, researchers developed grooved microneedles made from hyaluronic acid for precise transdermal drug delivery, achieving accurate dosage with a high probability of delivery (98% or more) by using an easy-to-operate applicator for shearing force.

This study found that while Sudanese women had good awareness of hormonal contraceptives, they lacked knowledge about emergency contraceptives and non-family planning benefits, with side effects like hair loss influencing their attitudes.

This study systematically reviewed the use of topical testosterone products such as creams, gels, and patches, finding they effectively raise serum testosterone but pose significant systemic risks like acne and gynecomastia, necessitating careful medical oversight.

This study reports that a novel ketoconazole-loaded microneedle array significantly enhances drug delivery and retention in the skin, demonstrating improved hair growth in animal models, suggesting a promising treatment for androgenic alopecia that addresses current topical therapies' limitations.

In this review, recent advances in long-acting microneedle-based transdermal drug delivery systems are outlined, highlighting biodegradable polymers like PLA, PLGA, and PCL for sustained release and discussing challenges in clinical translation such as consistency in manufacturing and validating long-term efficacy and safety.

This study developed a nanoemulsion containing Minoxidil, which showed effective stability and significantly increased hair growth rates in pretreated mice, suggesting its potential for treating hair loss.

This study highlights the clinical potential of microneedles as an innovative transdermal drug delivery system for treating various skin diseases with minimal pain and high patient compliance.

Transethosomes improve drug delivery through the skin and show promise for treating various conditions.