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This study found that in Colombian women with non-scarring alopecia, decreased serum ferritin levels were associated with telogen effluvium, but no such link was observed with thyroid disorders.

The research observed that 40-nm self-assembled nanoparticles enhanced minoxidil penetration in hairy guinea pig skin compared to 130-nm nanoparticles, but this size effect was absent in hairless skin.

In this study, researchers found that chitosan-coated PLGA nanoparticles improved the iontophoretic transdermal delivery of the positively charged hydrophilic drug donepezil hydrochloride in an ex vivo rat skin model, achieving 2.2 times higher skin accumulation compared to non-coated nanoparticles.

This review highlights recent advances in the design of nanocarrier systems for transdermal drug delivery, detailing their potential to improve treatment precision for dermatologic conditions despite challenges like formulation stability and scalability.

This review highlights recent advances in personalized transdermal drug delivery systems, noting their potential for improved treatment efficacy and safety, but identifies significant challenges in clinical translation.

This paper discusses ethosomal drug delivery systems, highlighting their improved ability to enhance skin penetration and increase therapeutic effectiveness in treatments like acyclovir for herpes labialis and minoxidil for androgenic alopecia compared to standard formulations.

This study reports that ethosomal formulations, such as ethosomal acyclovir and minoxidil, improved therapeutic effectiveness by enhancing skin permeation, leading to faster healing of herpes labialis lesions and increased skin absorption compared to standard formulations.

This review discusses the use of terpenes and invasomes as permeation enhancers for transdermal drug delivery, focusing on their potential applications in pharmaceutical formulations, but it reports no new experimental results.

This review discusses recent advances in skin penetration mechanisms, specifically focusing on the enhanced understanding of the follicular pathway and its implications for transdermal therapies, immune system targeting, and nanoparticle safety.

This study found that excipients significantly influence the effectiveness of curcumin nanocrystals in dermal applications, enhancing or hindering hair follicle targeting and passive diffusion based on their selection.

In this study, the researchers observed that the transdermal permeation mechanisms of diclofenac salts differ based on counterions, with varying pathways and routes for passive and iontophoretic transport.

This study found that cholesterol- and phospholipid-free multilamellar niosomes improved skin deposition and targeted deeper hair follicles better than hydrophobic PLGA nanoparticles for transdermal drug delivery.

This study found that smaller curcumin nanocrystals (60 nm) enhanced transdermal and transfollicular penetration more effectively than larger sizes, influenced by particle size.

Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.

This study found that finite element analysis-guided design improved bubble microneedles' controlled tip separation and insertion strength, supporting effective transdermal and sublingual drug delivery.

This study developed a co-design framework using finite element analysis to optimize bubble microneedles, achieving controlled tip separation and effective drug delivery through the skin and mucosa while maintaining insertion strength.

This review discusses therapeutic deep eutectic solvents as promising "green" solutions for enhancing drug solubility and delivery through the skin, reporting no new clinical results and highlighting future research directions.

This study developed dutasteride-loaded microneedle systems using a specific polymer to enhance transdermal delivery, demonstrating efficient drug release and increased accumulation in hair follicles, thus supporting their potential for treating androgenic alopecia.

This review outlines the potential of nanoemulsion-based hydrogels (nanoemulgels) for enhanced topical and transdermal drug delivery in treating skin disorders, highlighting their ability to improve therapeutic efficacy, control drug release, and boost patient compliance.

This review discusses the design strategies and applications of long-acting polymeric microneedles, noting their potential to improve patient compliance and reduce side effects in chronic disease management, but reports no new experimental results.

This study found that using elastic nano-liposomes to deliver palmitoylethanolamide improved its transdermal delivery and enhanced its skincare effects, with minimal cytotoxicity and no allergic reactions observed.

This review highlights recent advances in liposome-based transdermal drug delivery systems, emphasizing their potential to improve drug penetration for both skin and systemic diseases while discussing the challenges and future directions in this field.

This review highlights the potential of plant-derived natural compounds as biocompatible and biodegradable materials in dermal and transdermal delivery systems, emphasizing their unexplored benefits and detailing recent advances in isolation techniques and drug delivery technologies.

This article discusses the potential of novel microneedle transdermal systems for enhanced drug and vaccine delivery through the skin, but reports no clinical results and emphasizes ongoing trials.

This review discusses the potential benefits of using natural permeation enhancers to improve transdermal drug penetration in formulations like emulgel, a promising topical delivery system for hydrophobic drugs.

In this study, ethosomes were found to improve the skin penetration of a model lipophilic drug more effectively than liposomes or hydroethanolic solutions, suggesting a unique mechanism involving the breakdown of vesicles in the skin.

This study found that nanoemulsions of different sizes vary in their ability to penetrate skin layers, with smaller sizes aiding transdermal delivery and potential applications in transcutaneous immunization.

Ethosomes improve finasteride delivery through skin for hair loss treatment.

The study reported that combining the Follicular Closing Technique with the Franz diffusion cell is a valuable method for investigating follicular caffeine penetration in vitro, though kinetics differ from in vivo results.

This study found that nanocapsules formulated as a dispersion and applied with massage may enhance follicular uptake of clobetasol propionate while minimizing its skin penetration, offering a potential improvement over conventional treatments for scalp diseases.