Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, the gene SlPHL1 was identified as a transcription factor in tomatoes that enhances phosphate starvation responses by upregulating specific genes.

This study found that macrophages near hair follicles contribute to the activation of skin epithelial stem cells in mice, suggesting a novel role for macrophages in regulating hair growth.

This study found that Centipeda minima extract promotes hair growth by activating Wnt/β-catenin, ERK, and JNK signaling pathways in human hair follicle dermal papilla cells.

This study reports that miR-22 promotes cancer progression and metastasis by maintaining Wnt/β-catenin signaling and cancer stem cell function.

This study found that c-Jun is essential for vitamin D receptor expression, and the vitamin D receptor inhibits c-Jun-dependent cell death through non-classical mechanisms independent of vitamin D3.

In this study, the researchers optimized a method for culturing melanocyte precursors from hair follicles and found that 1,25-dihydroxyvitamin D3 significantly promotes their differentiation and melanin synthesis.

This study found that exogenous melatonin improved cashmere fiber quality and yield in goats by enhancing antioxidant capacity and reducing pro-aging cytokine expression in secondary hair follicles.

This review discusses the role of the TCL1 transgenic mouse model in understanding chronic lymphocytic leukemia biology and highlights the importance of exploring new pathogenetic and therapeutic targets.

This thesis investigates the role of phosphorylation and the mutation F826L in modulating androgen receptor activity, but concludes that the precise effects are not yet fully clear.

This study uses cryo-electron microscopy to reveal how androgen receptor forms a non-obligate dimer to bind DNA, with implications for prostate cancer development.

This article reviews the molecular mechanisms involved in androgenetic alopecia and the androgen's paradoxical role in hair growth, but reports no new experimental findings.

This review discusses the molecular mechanisms of androgens and androgen receptors in skin disorders, particularly androgenetic alopecia, and reports no new clinical results; it highlights potential areas for future treatment development.

This review examines the clinical features, causes, diagnosis, and treatment of Chrousos syndrome but reports no new experimental findings on this condition.

This study found that VEGFR-2 activation may play a role in hair follicle differentiation, proliferation, and apoptosis by co-expressing with several key proteins in normal human scalp skin.

In this study, a novel mutation in the glucocorticoid receptor gene was identified in a young woman, impairing glucocorticoid signaling and leading to generalized glucocorticoid resistance.

This study found that androgen receptor activation in adult mouse skin reduces β-catenin-induced hair follicle growth and sebaceous gland conversion, highlighting its role in stem cell fate decisions.

This study found that inhibiting AP-1 transcription factors in mice causes squamous tumors to transform into sebaceous tumors and regulates tumor cell lineage.

This narrative review explores how exercise might help maintain skin homeostasis disrupted by protein deficiency, potentially by promoting processes like increased collagen synthesis and stimulating anti-inflammatory effects, though the exact mechanisms are not entirely understood.

This study found that zebrafish and stickleback fish use similar genetic programs for tooth regeneration, despite differences in their dental structures.

This study found that Wnt signalling activates hair follicle fate in hair follicle stem cells by relieving TCF3/4–TLE-mediated repression, with β-catenin being crucial for this process.

This study found that direct co-culture of human bone marrow-derived mesenchymal stromal cells with regulatory T cells enhanced osteogenic gene expression, alkaline phosphatase activity, and matrix mineralization, suggesting Treg's potential in promoting bone regeneration by modulating BMSC mechanobiology through the ROCK-myosin signaling pathway.

This study found that topical bortezomib increased cell proliferation in hair follicles and sebaceous glands in mice and may activate hair keratin gene expression through GATA-3 transcription factors.

In this study, β-catenin overexpression in human hair outer root sheath cells increased the expression of Pitx2, which activated the follicular differentiation pathway, suggesting Pitx2's potential role as a modulator in hair growth control.

This paper describes the hGRα gene structure and its expression, focusing on the functional properties of the longest GRα isoform, but reports no new results.

This review discusses the regulation of involucrin gene expression, focusing on transcription factors and signaling pathways, and reports no new experimental findings.

This study found that in estrogen receptor-positive breast cancer cells, 17β-estradiol repressed polyamine oxidase transcription by interacting with AP-1 sites on its promoter.

This study reports that a new ROS-responsive hydrogel platform delivering miR-665 effectively reduced inflammation and promoted hair follicle regeneration in AA, suggesting a promising treatment approach.

This review discusses the composition, activation, and regulation of the JAK/STAT pathway and highlights its role and inhibitors in various diseases, but reports no new experimental results.

This study observed that direct exposure to androgens in Western clawed frogs differentially affects thyroid receptor and deiodinase gene expression in male and female tissues, offering insight into sex-specific metabolic pathway activation.

This study found that targeting the p300/androgen receptor axis effectively reduced AR activation and ovarian fibrosis in mouse models of polycystic ovary syndrome, suggesting a potential therapeutic approach.