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β-catenin is essential for stem cell activation and proliferation in hair follicles.

Hairless protein can block vitamin D activation in skin cells.

The vitamin D receptor can work without its usual activating molecule.

A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.

SIPHL1 from tomato enhances plants' response to low phosphate levels.

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.

A TP63 gene mutation causes significant hair loss and mild skin, nail, and tooth abnormalities.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

Minoxidil can reduce functions related to androgen receptors.

TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.

Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

MAD2B slows down the growth of skin cells that are important for hair development by interacting with TCF4.

A mutation in the hairless gene speeds up severe itchy skin in mice on a special diet.

ANp63 is crucial for skin integrity, new filaggrin gene mutations link to eczema, hair can regrow from non-stem cells, sunburns are increasing, and glucocorticoids help treat skin allergies by affecting immune cells.

Title change to "Central Centrifugal Cicatricial Alopecia (CCCA)"; common in African American women; hair-grooming methods may contribute; no effective therapy found; trials needed.

Androgens may block hair growth signals, targeting this could treat hair loss.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Reduced AR gene methylation may cause early pubic hair growth in girls.