Search
for

    Did you mean transdifferentiation?
    Glossary transdifferentiation

    mature cell changes directly into another mature cell type

    Transdifferentiation is a biological process where one type of mature cell transforms into another type of mature cell without first reverting to a stem cell state. For example, a skin cell might change directly into a nerve cell. This process is significant in regenerative medicine and tissue engineering because it offers potential for repairing damaged tissues and organs.

    Sort by

    Research 30 of 1000+

    1. Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals Proceedings of the National Academy of Sciences · 2005 · 130 citations
    2. Transdifferentiation of Human Hair Follicle Mesenchymal Stem Cells into Red Blood Cells by OCT4 Stem cells international · 2015 · 15 citations
    3. Transdifferentiation of corneal epithelium: evidence for a linkage between the segregation of epidermal stem cells and the induction of hair follicles during embryogenesis. The International Journal of Developmental Biology · 2004 · 55 citations
    4. Transdifferentiation of rat hair follicle stem cells to epithelium-like cells induced by stroma of limbus corneae Di-san junyi daxue xuebao · 2008
    5. Differential activity of 2-methylene-19-nor vitamin D analogs on growth factor gene expression in rhino mouse skin and comparison to all-trans retinoic acid PloS one · 2017 · 2 citations
    6. Phloem transdifferentiation from immature xylem cells during bark regeneration after girdling in Eucommia ulmoides Oliv Journal of Experimental Botany · 2008 · 44 citations
    7. Retinoic Acid-Induced Epidermal Transdifferentiation in Skin Journal of developmental biology · 2014 · 1 citations
    8. All-trans retinoic acid induced the differentiation of amelanotic melanocytes of human hair follicle Linchuang pifuke zazhi · 2004
    9. P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression Stem Cell Research & Therapy · 2016 · 24 citations
    10. Corneal epithelial‐like transdifferentiation of hair follicle stem cells is mediated by pax6 and β‐catenin/Lef‐1 Cell Biology International · 2009 · 20 citations
    11. Transcription factor-based transdifferentiation of human embryonic to trophoblast stem cells Development · 2024 · 4 citations
    12. Limbal microenvironment can induce transdifferentiation of hair follicle stem cells into corneal epithelial‐like cells Acta Ophthalmologica · 2008
    13. Corneal Limbal Microenvironment Can Induce Transdifferentiation of Hair Follicle Stem Cells into Corneal Epithelial-like Cells Stem Cells · 2008 · 162 citations
    14. [Differentiated application of oral contraceptives basing on the different side effects of synthetic progestins (author's transl)]. PubMed · 1976
    15. Tgm2/Gh, Gbx1 and TGF-beta are involved in retinoic acid-induced transdifferentiation from epidermis to mucosal epithelium The International Journal of Developmental Biology · 2011 · 14 citations
    16. Immunophenotypical analyses of myofibroblasts in rat excisional wound healing: possible transdifferentiation of blood vessel pericytes and perifollicular dermal sheath cells into myofibroblasts. PubMed · 2012 · 26 citations
    17. Two Opposing Faces of Retinoic Acid: Induction of Stemness or Induction of Differentiation Depending on Cell-Type Biomolecules · 2019 · 41 citations
    18. Label Retaining Cells (LRCs) with Myoepithelial Characteristic from the Proximal Acinar Region Define Stem Cells in the Sweat Gland PLoS ONE · 2013 · 36 citations
    19. Sox21 Regulates Anapc10 Expression and Determines the Fate of Ectodermal Organ iScience · 2020 · 22 citations
    20. Ligand-Independent Vitamin D Receptor Actions Essential for Keratinocyte Homeostasis in the Skin International Journal of Molecular Sciences · 2025
    21. Intravital imaging of hair-cell development and regeneration in the zebrafish Frontiers in Neuroanatomy · 2013 · 19 citations
    22. Ligand-Independent Vitamin D Receptor Actions Essential for Keratinocyte Homeostasis in the Skin 2024
    23. Cartilage to bone transformation during fracture healing is coordinated by the invading vasculature and induction of the core pluripotency genes Development · 2017 · 160 citations
    24. Signaling in the stem cell niche: regulating cell fate, function and plasticity Development · 2018 · 139 citations
    25. Cellular Plasticity in Cutaneous Wound Healing Biomedical Journal of Scientific & Technical Research · 2018
    26. Regulation of epidermal proliferation and hair follicle cycling by synthetic photostable retinoid EC23 Journal of cosmetic dermatology · 2023
    27. Network analysis reveals potential mechanisms that determine the cellular identity of keratinocytes and corneal epithelial cells through the Hox/Gtl2-Dio3 miRNA axis Frontiers in Cell and Developmental Biology · 2025
    28. Wound Healing: A Paradigm for Regeneration Mayo Clinic Proceedings · 2013 · 64 citations
    29. Insight into Reepithelialization: How Do Mesenchymal Stem Cells Perform? Stem Cells International · 2015 · 40 citations
    30. Epidermal stem cells: an update on their potential in regenerative medicine Expert opinion on biological therapy · 2013 · 9 citations