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    Did you mean Transepidermal Water Loss?
    Glossary Transepidermal Water Loss

    water evaporates from the skin's surface, indicating barrier function

    Transepidermal Water Loss (TEWL) refers to the process by which water passes from the inside of the body through the epidermis (the outermost layer of the skin) and evaporates into the environment. It is a key indicator of the skin's barrier function; higher TEWL values suggest a compromised skin barrier, which can lead to dryness, irritation, and conditions like eczema.

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    Research 30 of 1000+

    1. Effects of dietary camelina, flaxseed, and canola oil supplementation on inflammatory and oxidative markers, transepidermal water loss, and coat quality in healthy adult dogs Frontiers in Veterinary Science · 2023 · 7 citations
    2. LB948 AI-based customization in hair loss treatment: A 6-month clinical trial with transepidermal water loss and scanning electron microscopy analysis Journal of Investigative Dermatology · 2024
    3. Epidermis-specific ablation of claudin-1 in adult mice demonstrates the essential role of a tight junction barrier in skin homeostasis Journal of Dermatological Science · 2016 · 1 citations
    4. 599 Amelioration of symptoms of dry and eczema-prone skin by an oil-in-water emulsion containing a combination of a zingiber officinale root extract and cbd with antioxidative and anti-inflammatory activity in vitro Journal of Investigative Dermatology · 2023
    5. Loss of Keratin K2 Expression Causes Aberrant Aggregation of K10, Hyperkeratosis, and Inflammation 2014 · 32 citations
    6. Artificial Intelligence-Based Personalization of Treatment Regimen for Hair Loss: A 6-Month Clinical Trial. PubMed · 2025
    7. 393 Skin manifestations and biophysical properties in patients with morbid obesity and changes after weight loss: A two-year prospective study Journal of Investigative Dermatology · 2023
    8. Sequential Scalp Assessment in Hair Regeneration Therapy Using an Adipose-Derived Stem Cell–Conditioned Medium Dermatologic Surgery · 2019 · 33 citations
    9. Experimental and Clinical Efficacy of Two Hyaluronic Acid-based Compounds of Different Cross-Linkage and Composition in the Rejuvenation of the Skin Pharmaceutical research · 2014 · 20 citations
    10. Occlusion and hydration of scars: moisturizers versus silicone gels Burns · 2022 · 8 citations
    11. Treatment of periorbital aging with negative pressure fractional microneedle radiofrequency: A self‐controlled clinical trial Journal of Cosmetic Dermatology · 2023 · 4 citations
    12. A dietary supplement improves age-related dermatological changes. Observational, anecdotal, spontaneous study. Asian journal of medical sciences · 2017 · 1 citations
    13. The fatty acids and the skin: a focus on the n-6 family of unsaturated fatty acids Human health handbooks · 2012 · 1 citations
    14. POLEVAN®—A Multifunctional Natural Hair Ingredient, as Determined by In-Vitro and Human Studies Cosmetics · 2025
    15. Efficacy of <i>Thermus thermophilus</i> Fermentation Extract in Promoting Hair Growth and Improving Scalp Health in Androgenic Alopecia: A Clinical and In Vitro Study Journal of Cosmetic Dermatology · 2025
    16. Ligand-Independent Vitamin D Receptor Actions Essential for Keratinocyte Homeostasis in the Skin International Journal of Molecular Sciences · 2025
    17. Ligand-Independent Vitamin D Receptor Actions Essential for Keratinocyte Homeostasis in the Skin 2024
    18. The fatty acids and the skin: a focus on the n-6 family of unsaturated fatty acids 2012
    19. 25 Hydroxyvitamin D 1 α-Hydroxylase Is Required for Optimal Epidermal Differentiation and Permeability Barrier Homeostasis 2004 · 140 citations
    20. Stratum corneum dysfunction in dandruff International Journal of Cosmetic Science · 2012 · 93 citations
    21. Obesity resistance of the stearoyl-CoA desaturase-deficient (<i>scd1</i> <sup>-/-</sup>) mouse results from disruption of the epidermal lipid barrier and adaptive thermoregulation Biological Chemistry · 2007 · 87 citations
    22. Epidermal pigmentation in the human lineage is an adaptation to ultraviolet radiation 2013 · 62 citations
    23. Antioxidant and Cytoprotective Properties of Plant Extract from Dry Flowers as Functional Dyes for Cosmetic Products Molecules · 2021 · 48 citations
    24. Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid ω-Hydroxylase Crucial to Acylceramide Production Journal of Investigative Dermatology · 2019 · 40 citations
    25. An investigation of in vivo wound healing activity of biologically synthesized silver nanoparticles Journal of Nanoparticle Research · 2014 · 40 citations
    26. Age-Related Changes in Male Skin: Quantitative Evaluation of One Hundred and Fifty Male Subjects Skin Pharmacology and Physiology · 2013 · 40 citations
    27. Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole‐body energy expenditure The Journal of Pathology · 2016 · 38 citations
    28. Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation Journal of Allergy and Clinical Immunology · 2019 · 34 citations
    29. Caffeine improves barrier function in male skin International Journal of Cosmetic Science · 2006 · 33 citations
    30. The acyl-CoA binding protein is required for normal epidermal barrier function in mice Journal of Lipid Research · 2012 · 31 citations