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This study investigated dermal fibroblasts in mouse skin using single-cell RNA sequencing and identified signaling pathways that influence adipogenesis, finding that IL-1-NF-κB promotes, while WNT-β-catenin inhibits, the adipogenic potential of these cells, with implications for wound healing and scar formation.

This study found that prenatal exposure to fluoride and lead, as well as maternal micronutrient intake, may influence sexual maturation in adolescents in a sex-specific manner.

This study used single-cell RNA sequencing to characterize 19 distinct cell populations in sheep hair follicles, uncovering differentiation signatures and intercellular communication that may influence wool curvature and sheep breeding.

This source reports that the Indian Journal of Plastic Surgery received its first Journal Impact Factor of 0.8 for 2022, a notable achievement highlighting its significant contributions to the field of plastic surgery.

In this review, the authors discuss how niche-specific immunometabolic regulation influences tissue repair across various organs by highlighting the complex, context-dependent interaction between immune metabolism and tissue-specific regenerative outcomes.

This essay illustrates how individual patient choices, alongside advancing treatments, significantly influence alopecia areata management, underscoring the profound effect on patients' quality of life and self-identity.

This review compiles current research on the role of long non-coding RNAs in regulating muscle growth and regeneration processes, particularly their influence on Duchenne muscular dystrophy, and reports no new clinical results.

This study examined the cytodifferentiation stage of hair follicle development in cashmere goats, identifying nine cell populations and key regulatory pathways, including transcription factors and keratin genes, that may influence fiber quality and inform breeding strategies.

In this study, researchers found that human fingerprint ridges are formed through a modified hair follicle developmental process and spatial patterns influenced by specific signaling pathways.

This study used a probabilistic Boolean network model to explore hair follicle cell fate regulation and predicted that varying TGF-β levels, in coordination with BMP and TNF, can influence either apoptosis or cell proliferation during different follicle growth stages.

This review highlights how wound microbiota, particularly bacteria like Staphylococcus epidermidis and Staphylococcus aureus, significantly influences wound healing dynamics and suggests potential clinical applications through microbiota manipulation.

This study used cashmere goats to reveal distinct intermediate states of dermal papilla cells, each with specific roles in hair growth, shedding, and regeneration.

In this prospective cohort, baseline severity, disease activity, and relapse history were identified as key factors influencing response and recurrence in alopecia areata, suggesting that implementing standardized assessments could enhance risk stratification and personalized care approaches.

This review discusses the dynamic, niche-driven regulation of stem cell states in tissue homeostasis and regeneration, focusing on epithelial stem cells in the mammalian skin, intestine, and lung, without providing new experimental results.

This review explores the diverse roles and heterogeneity of fibroblasts across different organs, highlighting their potential involvement in both normal tissue functioning and fibrotic diseases, but reports no new experimental results.

This review addresses the effects of testosterone on brain development and examines both the established sex differences in brain functions and the debate surrounding structural dimorphism in neuropsychiatric conditions.

This review explores recent advancements in understanding how various physiological and psychological factors, such as stress and aging, influence epidermal stem cell populations, highlighting their importance in immune-related skin disorders and potential for clinical applications.

This essay discusses the role of the nail in mammalian digit tip regeneration and explores whether nail stem cells are solely responsible for this regenerative ability, with no new results presented.

The journal has grown significantly and is expected to continue succeeding under new leadership.

In this narrative review, the authors highlighted that AI-supported electronic health record analysis could help recognize Polycystic Ovary Syndrome/Polyendocrine Metabolic Ovarian Syndrome earlier, but also warned that these systems might perpetuate historical biases if not properly validated and interpreted.

This study examined sheltered and adopted domestic cats, finding that dark coat color and living environment significantly influence hair cortisol and DHEA levels as stress indicators, while age and sex do not; adoption was associated with reduced long-term stress, underscoring its benefits for feline welfare.

In this study, researchers using QM/MM simulations identified key molecular motions and residue interactions in the enzyme SRD5A2 that significantly influence its catalytic efficiency, demonstrating that specific residues play critical roles in stabilizing transition states and reducing activation barriers.

Natural products might help treat hair greying.

This review examines the interconnected processes of atopic dermatitis and alopecia areata, highlighting shared immune imbalances, genetic factors, and microbiome influences, while analyzing current and emerging treatments and identifying gaps in understanding these overlapping conditions.

Using a multi-omics analysis, this study identified key regulators like PLA2G12A, KRT79, and prostaglandin B2 that influence cashmere fineness, providing crucial data for understanding the molecular mechanisms behind this trait in Liaoning cashmere goats.

Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.

This study created a detailed spatial atlas of healthy human skin and basal cell carcinoma, revealing a potential hair follicle origin for basal cell carcinoma and expansion of certain mesenchymal cell populations.

This study mapped a detailed genetic profile of goat hair follicle apoptosis, identifying key genes and regulatory factors involved in the hair cycle, offering new insights into programmed cell death.

In this study, researchers found that electrospun membranes with aligned surface topography advanced the immune response towards an adaptive stage and highlighted the role of T cells in hair follicle regeneration in mice, showcasing the intricate interactions between immune and skin cells.

This study used single-cell RNA sequencing to map the cellular composition of sheep hair follicles, revealing differentiation pathways and potential molecular mechanisms for wool curvature, which may inform sheep breeding.