April 2026 in “Trends in Sciences” This study found that Acanthus ebracteatus extract may promote the proliferation of human hair follicle dermal papilla cells and reported that its microemulsion was stable for 12 weeks.
March 2026 in “Dermatopathology” This study found that sebaceous gland-derived cutaneous adnexal carcinomas exhibited the highest frequency of genomic alterations compared to other tumor types.
March 2026 in “Experimental Dermatology” This study developed an in vitro model using NTERT keratinocytes expressing AEC-related TP63 mutations, which replicated skin defects observed in AEC patients and offers a valuable tool for understanding the disorder and developing new treatments.
October 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In a study on secondary hair follicle stem cells from Arbas cashmere goats, researchers found that 10 μg/mL quercetin for 48 hours enhances cell proliferation and inhibits apoptosis through multiple signaling pathways, potentially improving cashmere production.
May 2025 in “Experimental Dermatology” This study found that specific TRPM5 modulators are unlikely to directly affect sebaceous glands, but safe TPPO analogues may provide moderate lipogenic and anti-inflammatory effects beneficial for dry skin conditions.
April 2025 in “BMC Urology” This case report highlighted a rare occurrence of both adrenocortical carcinoma and uric acid kidney stones in a 5-year-old boy, with hormonal levels and clinical symptoms returning to normal after treatment and no recurrence over four years, emphasizing comprehensive endocrine evaluations in pediatric ACC management.
November 2024 in “Journal of Investigative Dermatology” Serotonin helps wounds heal faster.
June 2024 in “Research Square (Research Square)” This case report documented a 32-year-old man's acute pancreatitis following an overdose of finasteride, highlighting the potential for rare but severe side effects from the drug in overdose situations, and suggesting a need for further research into its safety.
This study suggests that Myrtus communis shows promising effects for various conditions like GERD, menstrual bleeding, and wound healing in clinical trials, though some adverse effects may occur with systemic administration of myrtle essential oil.
December 2023 in “International journal of ophthalmology” This study found that minimally invasive combined fascia sheath suspension improved eyelid symmetry in patients with unilateral ptosis, particularly in measures of marginal reflex distance and eyelid contour.
November 2023 in “Ibrahim Cardiac Medical Journal” This study observed that patients with alopecia areata have a significantly higher prevalence of thyroid disorders and elevated levels of thyroid-stimulating hormone and thyroid auto-antibodies compared to healthy individuals, with a 4.7 times greater risk of thyroid dysfunction among alopecia areata patients.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, mice lacking the Mcpip1 gene in their myeloid cells did not develop SCC-like tumors but instead showed increased melanocyte activity and hair loss, indicating a distinct role for myeloid Mcpip1 in skin cancer development compared to keratinocyte Mcpip1.
October 2023 in “International journal of molecular sciences” In this study, researchers analyzed the skin proteome of Alpine Merino sheep to identify proteins and pathways related to wool fiber diameter, finding that cyclic adenosine monophosphate and certain signaling pathways may play a role in this trait.
September 2023 in “Biomedical Optics Express” This study used non-invasive imaging techniques to assess hair follicle characteristics in AGA mice, revealing delayed hair shaft alternation and growth stages, as well as testosterone-induced follicle miniaturization, offering potential methods for evaluating AGA on human scalps in vivo.
October 2022 in “International journal of dermatology and venereology” This case report describes novel trichoscopic features of anagen effluvium caused by azathioprine in a patient with normal TPMT levels, emphasizing the importance of regular monitoring for adverse effects.
May 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that TET2 plays a tumor-suppressive role in preventing squamous cell carcinomas by regulating 5-hydroxymethylcytosine levels, suggesting therapeutic potential for DNA methylation dynamics.
February 2022 in “Journal of Armed Forces Medical College” This case report details a patient with autoimmune hypothyroidism who experienced multiple health issues that improved with comprehensive treatment including Thyroxin replacement and other supportive measures.
May 2020 in “Research Square (Research Square)” This study found that trichilemmal carcinoma shares genetic changes with other skin cancers, suggesting a similar pathogenesis, particularly in those with aggressive clinical courses linked to TP53 mutations.
April 2020 in “Research Square (Research Square)” This study reported genetic mutations in trichilemmal carcinoma similar to those found in other skin cancers, including TP53 mutations associated with aggressive disease.
September 2019 in “Journal of Investigative Dermatology” This qualitative study found that healthcare professionals view psychosocial needs as a major reason for offering therapeutic education and self-management support for psoriasis, but efficacy remains uncertain.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that treating human skin explants with TPA increased the number of certain melanocyte phenotypes in the interfollicular epidermis, suggesting that this ex vivo model can effectively replicate human skin's pharmacologic responses for studying potential treatments.
April 2017 in “Journal of Investigative Dermatology” In laboratory tests and mouse models, this study found that the novel IPC analog SIG-1451 may offer potent anti-inflammatory effects for treating allergic skin inflammation, potentially outperforming some current therapies in specific inflammatory phases.
April 2017 in “Our Dermatology Online” This case study identified a 22-year-old patient with multiple autoimmune syndrome type 3, involving lupus erythematosus, autoimmune thyroiditis, alopecia areata, and vitiligo.
April 2016 in “Journal of Investigative Dermatology” This study found that adding cell adhesion-linked gene expression variables improved the identification of patients with SLN metastases within 90 days of melanoma diagnosis compared to using clinicopathologic variables alone.
April 2016 in “Journal of Investigative Dermatology” Mutations in the TSPEAR gene cause a new form of ectodermal dysplasia affecting hair and tooth development.
This study found that bursts of ERK activation in the epidermis of mice were linked to cell division, supporting synchronized cell proliferation and transient ERK activity in living tissues.
October 2014 in “Cancer research” This study found that targeting mTORC1 with rapamycin effectively inhibited skin tumor promotion in a mouse model, highlighting a potential target for cancer chemoprevention.
April 2012 in “Cancer Research” This study found that Stat3 influences the differentiation and migration of keratinocytes, potentially impacting epithelial carcinogenesis, by examining Stat3 activation or deletion effects in mouse models.
April 2012 in “Cancer research” In this study, the authors found that targeting mTORC1 with rapamycin inhibited TPA-induced skin tumor promotion by affecting keratinocyte proliferation, including critical stem cell populations in the mouse epidermis.
September 2007 in “The American Journal of Gastroenterology” This case report illustrates that Systemic Lupus Erythematosus can lead to severe malabsorption, weight loss, and small bowel inflammation, requiring recognition for effective treatment and improved outcomes.