March 2012 in “Daehan hwajangpum hakoeji/Daehan hwa'jangpum haghoeji” This study observed that a cream containing functional compounds from medicinal plants increased collagen production in human skin, while a hair tonic enhanced hair growth in mice.
April 2008 in “Annals of General Psychiatry” This study found that social isolation in rats enhanced the effects of ethanol on certain brain steroids, increased GABAA receptor subunits, and amplified ethanol's inhibitory effects on seizures.
January 2023 in “Han'gug mi'saengmul saengmyeong gong haghoeji/Han-guk misaengmul saengmyeong gonghak hoeji” This study found that a mixed extract of N. jatamansi, O. basilicum, and C. sativus, particularly when extracted via steaming and ultrasonic methods, increased antioxidant content, stimulated melanin production for black hair, and promoted hair growth in mouse models, while maintaining high cell viability.
13 citations
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December 1977 in “Journal of Toxicology and Environmental Health” This study found that exposure to heated phenyl glycidyl ether vapor caused alopecia and skin lesions in rats but not in dogs.
October 2005 in “CRC Press eBooks” Telogen effluvium is a condition where hair falls out due to various factors like illness, stress, or nutrient deficiency.
12 citations
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December 1951 in “Experimental Biology and Medicine” This study found that feeding desiccated whole liver to immature rats on a synthetic diet largely prevented the negative effects of toxic cortisone acetate doses, unlike known B vitamins.
January 2026 in “Biospecies” In this study, a hair tonic containing black fungus extract was shown to have antifungal activity against Malassezia furfur, with the 70% extract concentration providing the strongest effect.
June 2025 in “Journal of Cosmetic Dermatology” In this study, a shampoo and hair tonic containing the botanical extract blend Asacurin100 reduced hair loss and improved scalp health in 35 male participants with androgenetic alopecia, without serious side effects, suggesting potential efficacy that warrants larger trials for confirmation.
September 2024 in “Journal of the American Academy of Dermatology” Botulinum toxin is not effective for treating male hair loss.
August 2024 in “Archives of Dermatological Research” This study found that in male patients with androgenetic alopecia, combining botulinum toxin type A with 5% Minoxidil significantly improved hair growth, patient satisfaction, and quality of life over six months, compared to using Minoxidil alone, without causing adverse effects.
September 2024 in “Journal of the American Academy of Dermatology” Botulinum toxin is not effective or cost-efficient for treating male pattern baldness.
January 2019 in “Prosiding Program Kreativitas Mahasiswa” This study found that a 15% Pisum sativum extract concentration in hair tonic showed the most effective hair growth, with a length of 14.51mm and weight of 0.16g.
6 citations
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May 2016 in “British Journal of Dermatology” This study reports the effective use of botulinum toxin A in treating multiple facial apocrine hidrocystomas in a 29-year-old man, a case not previously documented in English-language literature.
4 citations
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August 2022 in “Aesthetic Surgery Journal” This study found that one session of intradermal botulinum toxin type A injection decreased scalp sebum secretion and perception of greasiness more effectively than saline for up to 3 months.
2 citations
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August 2024 in “International Journal of Applied Pharmaceutics” This study found that a hair tonic containing 40% broccoli stalks extract was more effective in promoting hair growth in male white rats compared to lower concentrations, while also maintaining stable physical characteristics and safety during testing.
1 citations
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September 2022 in “KnE medicine” This study demonstrated that a nanoemulsion hair tonic containing 7% candlenut oil accelerated hair growth more effectively in Mus musculus than both lower concentrations and a commercial ginseng tonic.
June 2023 in “Journal of Pharmaceutical and Health Research” In this study with guinea pigs, a hair tonic containing 0.001% caffeine significantly stimulated hair growth, showing higher effectiveness with an average hair length of 18.294 mm compared to a tonic with 0.005% caffeine concentration, which resulted in an average hair length of 16.610 mm.
July 2022 in “Forte Journal” In this study, researchers tested hair tonic formulations with varying concentrations of bitter melon extract and found that higher concentrations enhanced hair growth in rabbits, with the 15% extract showing the greatest effect without causing skin irritation.
December 2020 in “Jurnal Kedokteran Hewan” In this study, researchers found that cayenne leaf extract significantly enhanced hair length and quantity in mice, with a 10% concentration being the most effective for stimulating growth.
November 2025 in “Andalas University eThesis (Andalas University)” This study found that a rosemary extract hair tonic at concentrations up to 15% effectively promotes hair growth in male Wistar rats, achieving longer and thicker hair compared to minoxidil 2%, and causing fewer side effects.
April 2025 in “Jurnal Analis Farmasi” This study evaluated hair tonic formulations containing Ambon banana peel extract and found that the preparation, particularly at an 8% concentration, significantly promoted hair growth compared to other formulations, though it still differed from the control group's effectiveness.
June 2024 in “Deleted Journal” This study explored the effects of hair tonics made from a combination of kelor leaf and fragrant pandan leaf ethanol extracts on rat hair growth, finding that these combinations influenced hair growth when compared to single extract formulations over 28 days.
January 2024 in “Jurnal Ilmiah Ibnu Sina (JIIS) Ilmu Farmasi dan Kesehatan” In this study, researchers developed a hair tonic using shallots (Allium cepa L.) and found that its F2 formulation was as effective as the positive control in promoting hair growth on the 21st day and remained stable over 28 weeks of testing.
28 citations
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January 2016 in “RSC Advances” This study found that non-toxic polycarboxylic acids can achieve satisfactory hair perming effects with limited strength loss, suggesting they have potential as a safer alternative to harmful perming chemicals.
1 citations
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September 2021 in “Dermatologic Therapy” The researchers reported that intralesional botulinum toxin A effectively alleviated pain associated with cutaneous leiomyomas in a patient with hereditary leiomyomatosis and renal cell cancer syndrome, with repeated treatments every three months maintaining pain relief over 1.5 years.
4 citations
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August 2014 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” In this study, the Narasoo healing shampoo and Hair tonic were associated with improvements in scalp hydration, hair gloss, and hair growth, but further research is recommended to confirm these effects.
March 2024 in “Journal of Evidence-Based Integrative Medicine” This study found that a hair tonic containing 1% teak leaf extract significantly increased hair growth and user satisfaction in men with androgenic alopecia after 24 weeks, without causing adverse effects, and was comparable to the standard treatment, minoxidil.
October 2022 in “Asian journal of healthy and science” This study found that a 20% concentration of mother-in-law's tongue leaf extract promoted hair growth in male rabbits, with effectiveness comparable to a positive control.
November 2025 in “Mendeley Data” This study outlines a randomized trial investigating the effects of botulinum toxin administered before hair transplantation to potentially improve outcomes by enhancing blood flow and reducing graft failure due to ischemia in androgenetic alopecia patients.
May 2021 in “Indian journal of forensic medicine and toxicology” This study found that excessive consumption of cloves in mice caused toxic changes in the liver, including structural damage and cell death, but concluded these effects are not considered dangerous.