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Skin aging reflects overall body aging and can indicate internal health conditions.

In this study, extracting internal lipids from Caucasian hair fibers led to decreased water permeability, influenced by the fluidity of lipids.

This study found that oral finasteride increased the total number of hairs in men with androgenetic alopecia by 55% over 2.5 years, but did not reduce the number of miniaturized vellus hairs.

This source highlights that alopecia areata is a complex autoimmune disorder leading to patchy, nonscarring hair loss with variable treatment responses, reflecting unmet clinical needs. Advances in genetic research are improving understanding, yet current treatments often lead to persistent relapses.

This article examines how digital technologies, drawing on Marshall McLuhan's concept of media as an "extension of man," transform design thinking by creating new possibilities without replacing it, emphasizing the need for a hybrid, reflective practice in design.

In this article, the author explores how digital technologies can expand the cognitive and creative capabilities of designers, noting that while technology transforms design thinking, it does not replace it but rather opens up new possibilities and requires a hybrid, reflective practice.

In this study, baseline neutrophil-to-lymphocyte ratio (NLR) was associated with predicting early trichoscopic response in patients undergoing PRP-based treatment for non-scarring alopecia.

This study found that elastin-like recombinamer (ELR) wound dressings promote tissue regeneration and stability without rejection in ex vivo and in vivo models, indicating potential for hard-to-heal wound treatment.

This study found that cetaceans have adapted their fibroblast growth factors to assist in low bone density, hypoxia tolerance, and the development of rigid flippers, reflecting significant evolutionary changes for aquatic life.

This study suggests that mammalian hair follicles may serve as a viable and non-invasive system for diagnosing traumatic brain injury, reflecting similar molecular responses observed in other tissues.

This study found that cortisol levels, a biomarker of chronic stress, significantly increased in the post-COVID-19 lockdown period compared to pre-lockdown and during-lockdown periods, especially among females and young adults, reflecting sustained psychological stress from the pandemic.

This case study describes a rare instance of subacute cutaneous lupus erythematosus on the chin, highlighting the effectiveness of using dermoscopy and reflectance confocal microscopy for accurate diagnosis and monitoring, which led to significant lesion improvement with corticosteroid and immunomodulatory treatment over 19 weeks.

This case report discusses a young woman who developed bilateral osteonecrosis of the femoral head after corticosteroid treatment for alopecia areata, underscoring the risk of this complication in patients undergoing such therapy.

The authors concluded that their new grading system can effectively classify early female pattern hair loss and evaluate treatment progress.

This study reported that fermented grapeseed oil may enhance hair permeability and improve strength and color retention in chemically treated hair compared to regular grapeseed or silicone oils.

This review discusses the 2023 International Guideline for PCOS assessment and management, highlighting updated evidence-based recommendations and practice points aimed at improving care and health outcomes, but notes that research quality remains generally low to moderate.

This study evaluated the efficacy of polyphenolic compounds for hair growth in adults with non-scarring alopecia and found that these interventions significantly improved hair density and total area hair count compared to controls, although results were not significantly different from minoxidil.

This study found that shampoo and conditioner do not alter hair's molecular structure, while perming treatments significantly affect keratin and intermediate filament structures due to bond alterations.

This review categorizes 59 modifications of the Dermatology Life Quality Index across multiple studies, highlighting the need for further validation of these customized health-related quality of life tools in dermatology.

This systematic review provides an in-depth evaluation of non-invasive imaging and biophysical methods for diagnosing and monitoring vitiligo, emphasizing the need for studies with larger sample sizes to verify their use in clinical practice and research.

This article reviews the use of hair cortisol concentration as a biomarker to assess long-term stress in both animals and humans, but it reports no new experimental results.

In this systematic review and meta-analysis, methotrexate and leflunomide were compared for treating rheumatoid arthritis, showing similar efficacy overall. Methotrexate reduced swollen joints more effectively, while leflunomide was associated with fewer gastrointestinal side effects but more frequent liver enzyme increases.

This study found that patients with Alopecia Areata, particularly those with severe forms, exhibited higher triglycerides, cholesterol, and low-density lipoproteins, suggesting increased cardiovascular risk factors.

This study found a significant association between patients' sex of rearing and external genitalia in those with gonadal dysgenesis, while noting lower testosterone levels compared to controls.

In this study, men using 2% and 5% minoxidil solutions experienced a significant increase in hair weight for 96 weeks compared to placebo, with effects diminishing after treatment cessation.

This study used ultrahigh-resolution optical coherence tomography to observe hair shaft structures, finding melanin granules absent only in white hair, which may explain color differences between black and white hair.

This review concludes that global literature supports the lipidosterolic extract of Serenoa repens as efficacious and safe for treating lower urinary tract symptoms, with some studies showing equivalence to common pharmacologic agents.

This review discusses topical calcineurin inhibitors for cutaneous lupus erythematosus and reports no new clinical findings; the authors emphasize the need for more comparative studies with corticosteroids.

This review discusses the isolation, characterization, and potential clinical applications of tissue-derived extracellular vesicles in cancer diagnosis, prognosis, and treatment, noting their significance but highlighting the risks and need for appropriate protocols.

The Journal für Ästhetische Chirurgie expanded its board to improve collaboration and knowledge in aesthetic surgery.