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The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

The document concludes that hair loss is common and can be treated with medications like minoxidil or surgical options, and it significantly affects people's psychological well-being.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Finasteride may cause kidney damage.

COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.

Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Obesity may contribute to female hair loss by increasing male hormone levels that affect hair follicles.

Jagged1 and Epidermal Growth Factor together significantly increased hair growth in mice with androgen-suppressed hair.

Finasteride negatively affects fish reproduction and gonadal development.

Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.

Bald men may have a lower risk of testicular cancer.

New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.

The document concludes that diagnosing PCOS requires a thorough approach, considering various symptoms and risks, and calls for improved methods to identify PCOS types and prevent diabetes.

Men with low or no sperm count have lower salivary testosterone levels, and saliva testing can measure their testosterone well.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Eating healthy, exercising, and changing behaviors are the best first steps to treat Polycystic Ovary Syndrome (PCOS).

Diagnosing Polycystic Ovary Syndrome is hard due to varying symptoms, no set criteria, and the need for better tests and education.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Hair loss causes differ between men and women due to changes in hormone levels and inflammation-related pathways.

Baldness, especially at the front, may lower the risk of testicular cancer by 31%, but its link to prostate cancer is unclear.

Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.

Finasteride safely treats enlarged prostate and male-pattern baldness.

Most types of hair loss can regrow naturally, but there are no effective cures for male pattern or age-related hair loss, and only limited options for females.

Curcumin improved some metabolic factors in women with PCOS but did not affect cholesterol, insulin, or testosterone levels.

Doctors should diagnose hair loss by examining the patient and possibly doing tests, and then treat it based on the type, which may prevent permanent hair loss.

Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.