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New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

Lipases, especially gehB, are crucial for Staphylococcus aureus to enter and colonize hair follicles.

Improving how drugs are absorbed through the skin could better treat mange in wombats.

Different immune cells like platelets, mast cells, neutrophils, macrophages, T cells, B cells, and innate lymphoid cells all play roles in skin wound healing, but more research is needed due to inconsistent results and the complex nature of the immune response.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

Early NAS level changes affect alcohol consumption vulnerability.

Hair growth is cyclic and influenced mainly by local factors.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Stem cell self-renewal is complex and needs more research for full understanding.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Fat cells are important for tissue repair and stem cell support in various body parts.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Cellular and immunotherapies show promise for healing chronic wounds but need more research.