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CRISPR/Cas9 gene-editing may effectively treat hair loss but requires more research for safe use.

Enzymes play crucial roles in metabolism, health, and disease management.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

A surface with VEGF can specifically capture endothelial cells from flowing fluids.

Standardized procedures are crucial for collecting and preparing biological samples to ensure accurate clinical metabolomics results.

Oxidative stress is linked to mild patchy alopecia areata.

Acne patients have higher levels of oxidative stress, but it's not clear if it causes or results from acne; antioxidants might help treat acne.

Popliteal Artery Entrapment Syndrome (PAES) is a rare but possible cause of leg pain during walking, even in untrained women.

Eosinophilia-myalgia syndrome, linked to contaminated L-tryptophan supplements, caused severe symptoms and some deaths, with long-term effects in survivors.

Oxidative stress increases in early hair loss, and family history plays a role; antioxidants may help future treatments.

The Spanish version of the Hair Specific Skindex-29 scale is a reliable and valid way to measure the impact of hair loss on women's quality of life.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Certain groups may need vitamin supplements to improve hair health and prevent other health problems.

Frontal Fibrosing Alopecia in men is often missed and can come with symptoms like facial bumps and hair loss on eyebrows and limbs.

Women with PCOS have higher xanthine oxidase activity linked to inflammation and heart disease risks.

Dermoscopy is a good, noninvasive way to see normal cat skin structures and could be useful for check-ups.

Trichoscopy helps diagnose hair and scalp disorders in dark-skinned people by identifying unique patterns.

Higher androgen levels do not cause baldness in men.

Heat damages hair, with Asian hair losing more protein than Caucasian hair.

Proper skin toxicity management in chemotherapy is key to continuing treatment and keeping patient quality of life high.

Recognizing and treating early signs of insulin resistance can help prevent type 2 diabetes and improve life quality.

In 2017, Spanish dermatologists most often prescribed minoxidil and finasteride for male hair loss, and minoxidil and oral contraceptives for premenopausal female hair loss.

Most white Spanish women have a widow's peak, and their hairline measurements could help in hair restoration surgery.

Podcasting could improve dermatology education if it had more consistent, evidence-based content and better regulation.

Eating less and exercising more, with personalized diet plans and realistic goals, can lead to weight loss and better health, but more research is needed for long-term success.

Finasteride can cause sexual dysfunction, sperm changes, and affect bone density and metabolism.

Bald men may have a lower risk of testicular cancer.

A man developed a rare cancer on his scalp after a hair transplant possibly due to sun damage, laser effects, and inflammation.