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The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Targeting hair follicles can improve skin treatments and reduce side effects.

Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.

Minoxidil works better than nitroglycerin for treating impotence with fewer side effects.

The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.

Cyclosporin A promotes hair growth in mice and increases a protein linked to hair growth, but it may not work the same way in humans.

Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.

Thuja orientalis hot water extract may help hair grow by starting the growth phase and improving hair follicle development.

400 nm particles penetrate hair follicles best, but mouse models aren't fully reliable for human studies.

Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.

Cedrol from Platycladus orientalis leaves may promote hair growth effectively, especially in female mice.

Olive leaf compound oleuropein helps grow hair in mice.

CARI ONE helps start hair growth and makes hair follicles bigger and more numerous.

A mix of Platycladus orientalis leaf extract and alpha-terpineol helps mice grow hair by increasing growth factors and cell growth.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

A new drug delivery system using oil body-bound oleosin-rhFGF-10 improves wound healing and hair growth in mice.

A substance called sodium zinc dihydrolipoylhistidinate can significantly reduce hair loss caused by chemotherapy in rats.

A herbal mix with chickpea, holy basil, and nut grass extracts grew rat hair well, similar to a common hair growth drug.

Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.

Fisetin may help treat psoriasis and reduce skin inflammation.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

Lipophilic dyes accumulate more in hair follicles when delivered with surfactant-propylene glycol solutions.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

Gray hair regained color after thyroid hormone treatment.

SM-215 promotes hair growth by improving the environment around hair follicles.

QMSI is a valuable method for studying drug penetration in skin tissues.

PBMCsec can help reduce and improve thick skin scars.

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

The compounds tested could potentially treat hair loss and alopecia.

Nanomaterials can improve hair care products and treatments, including hair loss and alopecia, by enhancing stability and safety, and allowing controlled release of compounds, but their safety in cosmetics needs more understanding.