research Physical Methods for Topical Skin Drug Delivery: Concepts and Applications
New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
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research A Phase 1 Study to Investigate the Effects of Cortexolone 17α-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity
Clascoterone is safe for the heart, even at high doses.
research Advanced Nanocarrier- and Microneedle-Based Transdermal Drug Delivery Strategies for Skin Diseases Treatment
Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
research Diagnosis of Hair Disorders
The document concludes that accurate diagnosis of hair disorders is crucial and requires a range of diagnostic methods.
research Percutaneous Absorption of a New Antiandrogen Included in Liposomes or in Solution
Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.
research Preventive Effects of Cedrol Against Alopecia in Cyclophosphamide-Treated Mice
Cedrol may prevent hair loss caused by chemotherapy better than minoxidil.
research Dermatology
Skin diseases are common and can significantly affect people's lives; better outcome measures and ethical clinical trials are needed to improve dermatology care.
research The Increasing Importance of the Hair Follicle Route in Dermal and Transdermal Drug Delivery
Using hair follicles can improve skin drug delivery.
research Follicular and Percutaneous Penetration Pathways of Topically Applied Minoxidil Foam
Minoxidil foam enters hair follicles and skin for hair growth.
research Drug Delivery with Topically Applied Nanoparticles: Science Fiction or Reality?
Nanoparticles show promise for drug delivery through hair follicles but not through healthy skin.
research Experimental and Early Investigational Drugs for Androgenetic Alopecia
New hair loss treatments may include topical medications, injections, and improved transplant methods.
research Topically Used Herbal Products for the Treatment of Hair Loss: Preclinical and Clinical Studies
Herbal products might promote hair growth with fewer side effects, but more research is needed to confirm their safety and effectiveness.
research Hair Follicle Targeting with Nanoparticles
Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.
research Follicular Transport Route: Research Progress and Future Perspectives
Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.
research Topically Applied Minoxidil May Cause Fetal Malformation: A Case Report
Minoxidil use during pregnancy may cause fetal harm.
research Topically Applied Minoxidil in Baldness
Minoxidil helps hair growth, but results vary.
research Topically Applied Nicotinamide Inhibits Human Hair Follicle Growth Ex Vivo
Nicotinamide applied to the scalp can slow down hair growth.
research Topically Applied Minoxidil in Baldness
Minoxidil, when applied to the scalp, can stimulate hair growth but effects vary, stop if treatment ends, and it may cause side effects like fluid retention.
research Permeation of Topically Applied Caffeine Through Human Skin – A Comparison of In Vivo and In Vitro Data
Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.
research Effect of Topically Applied Minoxidil on the Survival of Rat Dorsal Skin Flap
Minoxidil applied before and after surgery improves skin flap survival in rats.
research Permeation of Topically Applied Magnesium Ions Through Human Skin Is Facilitated by Hair Follicles
Hair follicles help magnesium get through the skin more effectively.
research Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles
The new "differential stripping" method effectively measures how much substance gets into hair follicles.
research Nanocarriers for Optimizing the Balance Between Interfollicular Permeation and Follicular Uptake of Topically Applied Clobetasol to Minimize Adverse Effects
Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.
research Somatotropin Penetration Testing From Topical Formulations Applied to the Skin
The new topical growth hormone formula has high skin penetration and bioavailability.
research Dermal Delivery of Topically Applied Oligonucleotides via Follicular Transport in Mouse Skin
Topical oligonucleotide therapy targets hair follicles effectively.
research In Vivo Response of GsdmA3Dfl/+ Mice to Topically Applied Anti-Psoriatic Agents: Effects on Epidermal Thickness, as Determined by Optical Coherence Tomography and H&E Staining
Betamethasone dipropionate reduced skin thickness, fish oil increased it, and combined treatment had no significant effect.
research (1R,2S)-4-(2-Cyano-Cyclohexyl-Oxy)-2-Trifluoromethyl-Benzonitrile, A Potent Androgen Receptor Antagonist For Stimulating Hair Growth And Reducing Sebum Production
The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.
research Can We Teach Old Drugs New Tricks? Repurposing Neuropharmacological Drugs for Inflammatory Skin Diseases
Old neuropharmacological drugs might be effective for treating inflammatory skin diseases.
research Transepidermal UV Radiation of Scalp Skin Ex Vivo Induces Hair Follicle Damage That Is Alleviated by Topical Treatment with Caffeine
Caffeine applied to the scalp can protect hair follicles from UV damage.
research On the Role of Melatonin in Skin Physiology and Pathology
Melatonin is important for skin health and protection, and can be made by the skin or applied to it.