1 citations
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January 2013 in “International Journal of Medicinal and Aromatic Plants” In a rabbit study, flaxseed oil applied topically significantly increased hair width, while flaxseed ingestion also had a positive effect, but neither method improved hair length or weight.
11 citations
,
March 2009 in “Bioorganic & Medicinal Chemistry Letters” This study reports that 4-(alkylthio)- and 4-(arylthio)-benzonitriles showed moderate sebum reduction as androgen receptor antagonists when applied topically in a validated animal model.
5 citations
,
April 2023 in “Bioengineering & Translational Medicine” This study found that STAR particles, when applied to human skin, were well tolerated and highly acceptable at various pressures and with repeated daily use, suggesting they may provide a safe and effective method for enhancing drug delivery through the skin.
15 citations
,
November 1983 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that testosterone propionate increased hair mass in female hamsters' flank organs, while cyproterone acetate applied topically reduced androgen-stimulated hair in a dose-dependent manner.
5 citations
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April 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this review, researchers noted that liposomes, due to their ability to stabilize and target drugs, are effective carriers for treating various dermatological conditions such as acne and psoriasis when applied topically.
July 2024 in “Journal of Investigative Dermatology” Topical thyroid hormones may boost hair growth.
January 2020 in “Medical Journal of Clinical Trials & Case Studies” This study found that topical minoxidil can be effective in preventing flap necrosis during latissimus dorsi flap reconstruction in patients who have undergone neoadjuvant chemoradiation.
3 citations
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January 2009 in “Medical Hypotheses” This study reports that topical iodine can initiate, control, and complete the regeneration of human scar tissue, with hair playing a key role in the process.
4 citations
,
January 1989 This study suggests that applying topical minoxidil may improve hair graft survival after hair transplantation by reducing post-operative shedding.
19 citations
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July 1993 in “Journal of Applied Toxicology” This study found that various petroleum distillates caused significant skin changes in mice, with severity varying based on the product and penetration pathway, potentially leading to skin tumors through non-genotoxic mechanisms in longer-term exposure.
December 2007 in “한국미용학회지” This study found that a complex oriental medicine extract applied topically promoted hair regrowth in mice with alopecia at a similar rate to 3% minoxidil.
April 2004 in “Inpharma Weekly” Melatonin helps hair growth in women with hair loss issues.
December 2023 in “Farmateka” Minoxidil is an effective and safe treatment for common hair loss when applied to the skin, but more research is needed for optimal use.
April 2023 in “Dermatology practical & conceptual” This study observed that a tacrolimus solution (0.1%) applied to the scalp was effective and well-tolerated for treating inflammatory scalp conditions, with 72.7% of patients showing an excellent response after 2 months of treatment, which persisted after 6 months.
March 2009 in “Journal of Biomedical Research” In this study, herbal extract mixtures applied to mice accelerated hair regrowth compared to a control group, suggesting potential hair-growing properties.
8 citations
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April 2017 in “International Journal of Dermatology” This study found that applying 5% topical minoxidil twice daily significantly increased nail growth rate in healthy participants compared to untreated nails, with effects observable from the first week.
44 citations
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October 2019 in “International Journal of Molecular Sciences” This article reviews various studies and suggests that melatonin, produced both naturally in the skin and applied topically, may offer significant protection against environmental damage, making it a promising candidate for skincare therapies.
25 citations
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January 1978 in “JAMA” This case report describes a 45-year-old woman who developed Cushing's syndrome and hirsutism after using topically applied desoximetasone (Topicorte).
5 citations
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February 2016 in “International Journal of Cancer” In this mouse study, applying a vasoconstrictor before chemotherapy did not create a leukemia sanctuary or significantly impact survival outcomes, suggesting it may not interfere with leukemia treatment.
3 citations
,
October 2018 in “Archives of Dermatological Research” This study suggests that the InlB321/15 protein may accelerate wound healing by increasing cell proliferation and reducing wound closure time in both cell culture and mouse models.
July 1996 in “Clinical and Experimental Dermatology” This study found that a single topical application of calcipotriol ointment did not affect systemic calcium levels in patients with chronic plaque psoriasis.
33 citations
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February 2021 in “Journal of Medicinal Chemistry” This study found that novel MPC inhibitor analogues with specific chemical modifications promoted significant hair growth in shaved mice when applied topically.
This study found that extract mixtures from certain Chinese herbs promoted hair growth in mice by inducing and prolonging the anagen phase when applied both intragastrically and topically.
January 2024 in “SAGE Open Medical Case Reports” This report describes the case of identical twin males, where one applied topical 5% minoxidil for over a year on the beard and mustache area and the other did not, highlighting the anecdotal use of minoxidil for facial hair enhancement.
October 2025 in “Journal of Craniofacial Surgery” In this study, microneedling followed by topical 2% chitosan significantly improved hair growth parameters in patients with androgenetic alopecia, comparable to results with 5% minoxidil, but a small sample size limits definitive conclusions on their relative efficacy.
2 citations
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October 2022 in “Journal of cosmetic dermatology” This study observed that a CBD-rich topical cannabis extract may increase hair count in patients with androgenetic alopecia when applied daily, but the effect is concentration-dependent and requires further research to establish safety and efficacy.
1 citations
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January 1994 in “Drug Development and Industrial Pharmacy” This study suggests that certain combinations of topical radioprotectors and vehicles can reduce radiation-induced hair loss in mice, with effectiveness varying by radiation dose and vehicle type.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that applying topical 6% gabapentin twice daily reduced disease activity and scalp pruritus in a patient with lymphocytic cicatricial alopecia, with no adverse effects reported.
November 1996 in “Inpharma Weekly” Lotion with piroctone olamine and triclosan improves hair loss in men.
61 citations
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May 2016 in “Scientific reports” This study found that IMT-P8, a novel cell-penetrating peptide, effectively facilitated the dermal delivery of proteins and peptides in mouse skin and cell lines, suggesting potential for topical applications in cosmetics and skin diseases.