2 citations
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October 2015 in “Indian journal of science and technology” This study found that SM-215 applied to mice increased hair follicle activity and capillary presence, promoting hair growth compared to non-treatment.
December 2022 in “Deleted Journal” In this study, topical application of keratin extract from wool promoted hair growth in mice by reducing the time for initiation and completion of growth phases and improving hair quality.
March 2022 in “International Journal of Health Sciences” In this animal study, topical pentoxifylline was associated with improved hair regrowth in cyclophosphamide-induced hair loss in male Swiss albino rats.
7 citations
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September 2004 in “대한의생명과학회지” This study suggests that a topical oriental medicine extract may improve hair density and scalp condition in individuals experiencing male pattern hair loss after 18 months of use.
April 2024 in “Biosaintifika Journal of Biology & Biology Education” In this study, researchers observed that a topical gel containing 20% hypoxia mesenchymal stem cell secretome significantly reduced IL-15 and IFN-γ mRNA expression and baldness by 60% in male Wistar rats with fluconazole-related alopecia.
5 citations
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December 2015 in “Dermatologic Therapy” In this study, topical phenylephrine significantly reduced hair shedding and increased the force needed to pluck hair in women undergoing cosmetic procedures, suggesting its potential utility for traction alopecia.
April 2023 in “Journal of Investigative Dermatology” In this study, topical inhibition of casein kinase 1 in mice was found to enhance melanocyte precursor migration and eumelanin production, suggesting potential applications for treating vitiligo and graying hair through KitL/c-Kit signaling pathway activation.
January 2018 in “International journal for pharmaceutical research scholars” In this study, topical application of tonic preparations containing 5% ethanol extract of Phyllanthus niruri to shaved mice showed potential as a hair growth enhancer, as indicated by observations of increased hair length and weight over a 21-day period.
76 citations
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July 2006 in “Veterinary Dermatology” In this pilot study, the researchers found that topical application of imiquimod 5% cream may significantly reduce equine sarcoid tumor size, with 80% of tumors showing more than 75% reduction.
December 2024 in “Journal of General-Procedural Dermatology & Venereology Indonesia” In this study, a topical hair growth serum containing ingredients like procapil and redensyl was found to be safe and effective for subjects with androgenic alopecia, significantly improving hair density, thickness, and Anagen:Telogen ratio after 120 days, with no observed adverse effects.
August 2025 in “Journal of the Korean Society of Cosmetology” In this study, a 5% Gymnema sylvestre leaf extract formulation applied to C3H mice showed significantly delayed hair regrowth by increasing TGF-β1 and TGF-β2 expression while reducing β-catenin levels, suggesting its potential as a natural hair growth inhibitor.
March 2023 in “Pakistan Journal of Medical & Health Sciences” This study found that alopecia areata patients often had low vitamin D levels, and topical calcipotriol treatment significantly reduced the severity of their hair loss.
10 citations
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August 2022 in “Bulletin of Mathematical Biology” This study demonstrated that the Turing bifurcation, typically a pitchfork bifurcation under zero-flux conditions, becomes transcritical under fixed boundary conditions, highlighting the importance of considering boundary condition variations in morphogenetic analyses.
September 2024 in “Journal of Skin and Stem Cell” In this study, a combination treatment of microinfusion (MMP®) and topical minoxidil showed a modest increase in hair density in a 28-year-old woman with chronic telogen effluvium, particularly in the parieto-vertex region, suggesting potential benefits but underscoring the need for larger trials to confirm efficacy.
October 2024 in “Clinical Cosmetic and Investigational Dermatology” This study documented successful use of Brevilin-A, a topical treatment, in pediatric patients with alopecia areata, indicating it as a potentially safe and effective option for managing mild-moderate cases and resistant forms of the disease.
September 2005 in “Journal of Investigative Dermatology” This study found that ferulic acid effectively stabilized vitamins C and E in a topical solution, doubling skin photoprotection against solar-simulated irradiation, which may help in preventing photoaging and skin cancer.
15 citations
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June 2019 in “Experimental Dermatology” The authors suggest that the neuroendocrine system of the skin represents a promising target for repurposing drugs, such as cannabidiol and fingolimod, as topical treatments for inflammatory skin diseases.
87 citations
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April 1973 in “Endocrinology” This study found that in hamster flank organs, 17βC inhibited enlargement caused by topical testosterone but not by DHT, suggesting potential use in androgen-related skin disorders like acne.
April 2026 in “Buletin Veteriner Udayana” In this case report, researchers observed that apple cider vinegar used as a topical antimicrobial agent effectively improved skin condition and reduced lesions associated with scabiosis and malasseziosis in a 3-year-old domestic cat, with noticeable results in 7 days.
1 citations
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January 2005 in “Experimental Dermatology” This study found that antisense oligonucleotides successfully reduced androgen receptor expression in human keratinocytes and reconstituted human epidermis, suggesting potential for developing topical treatments.
November 2025 in “Eduvest - Journal Of Universal Studies” This case report describes a young male patient with androgenetic alopecia who experienced significant hair growth improvement and no side effects after receiving single spin platelet-rich plasma therapy combined with topical minoxidil.
3 citations
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July 2019 in “International journal of scientific research in science and technology” This study found that a herbal gel containing fenugreek seed extract significantly promoted hair growth on mice after 30 days of topical application.
May 2023 in “Pharma innovation” In this study conducted at LFC, Apollo College of Veterinary Medicine in Jaipur, and on local farms, 20 cattle calves with ringworm infection fully recovered after treatment with a combination of 2% povidone iodine and Whitefield ointment applied for 15 days.
57 citations
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October 2013 in “international journal of endocrinology and metabolism” This review discusses clinical features, differential diagnosis, and treatments for female pattern hair loss, emphasizing the use of 2% topical Minoxidil and exploring alternative off-label therapies.
January 2025 in “Lasers in Medical Science” In this reported case, a 13-year-old boy with alopecia areata experienced complete lesion resolution and varied hair regrowth across different laser treatment parameters after three months of combined oral prednisone, topical ointment, and CO2 fractional laser therapy.
May 2023 in “Research Square (Research Square)” This study investigated the effects of HDDPiW-jSB solution on chemotherapy-induced alopecia in a rat model and found that the solution improved hair follicle health markers and reduced cell apoptosis, especially when applied twice weekly, while appearing safe for skin application.
January 2016 in “대한피부과학회지” This study found that a 0.5-mm microneedle depth was more effective than 0.3 mm for increasing hair density in AGA patients treated with a topical growth factor cocktail.
25 citations
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April 1949 in “The journal of experimental zoology” This research studied the effect of local testosterone propionate applications on rabbit epidermal mitotic activity but reports no new results.
78 citations
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February 2004 in “British Journal of Dermatology” This article reviews the potential impact of melatonin on hair growth, noting its benefits observed in animals, but reports no clinical results in humans to date.
May 2017 in “Journal of The American Academy of Dermatology” The new baby shampoo and wash with stearic acid is safe and potentially effective for nourishing babies' skin.