2 citations
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January 2011 This study found that topical 5% aqueous extract of Trichosanthes dioica R. leaves significantly promoted hair growth in rats compared to both a control and minoxidil treatment.
2 citations
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December 2024 in “International Journal of Pharmaceutics” In animal studies, this research found that minoxidil-loaded air-pocket microneedles improved hair loss treatment efficiency compared to topical application, while effectively sealing punctured skin openings.
2 citations
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May 2022 in “Cosmetics” This review explores the potential roles of the gut and skin microbiome in alopecia areata, suggesting topical and systemic strategies for managing the condition, but it reports no new clinical results.
1 citations
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November 2025 in “Journal of Education Health and Sport” This study suggests that cannabinoids, especially CBD, show promise as potential treatments for various inflammatory, infectious, and autoimmune skin diseases, with ongoing research needed to confirm clinical efficacy and safety.
1 citations
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November 2025 in “Journal of Cosmetic Dermatology” This source reports on ongoing clinical trials examining the therapeutic potential of topical CBD for skin conditions like acne, dermatitis, and psoriasis, and emphasizes that upcoming trial results will be crucial in evaluating its effectiveness.
1 citations
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March 2024 in “International Journal of Pharmaceutical Sciences and Drug Research” In this study on albino mice, Helianthus annuus and Martynia annua seed oil extracts in petroleum ether significantly promoted hair growth in a dosage-dependent manner, with 30 mg/ml showing notable results compared to 2% minoxidil.
1 citations
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October 2023 in “Journal of plastic, reconstructive & aesthetic surgery” This meta-analysis reported that stem cell-derived conditioned medium effectively increases hair density and thickness in patients with alopecia, with longer treatment durations showing greater improvements.
1 citations
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January 2023 in “Research Square (Research Square)” This study found that a neem-based herbal formulation may be more effective than ivermectin in treating sarcoptic mange in dromedary camels, leading to complete recovery without scarring or keratinization.
1 citations
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September 2017 in “Journal of Investigative Dermatology” This study reported that introducing the TERT and Bmi1 genes into mouse dermal papilla cells resulted in immortal cells capable of inducing new hair follicles in vivo, and human immortal DPCs were also developed.
1 citations
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April 2017 in “Journal of Investigative Dermatology” This study found that cilostazol promoted hair growth in human dermal papilla cells and mouse models, suggesting its potential as a therapeutic target for alopecia treatment.
1 citations
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January 2015 This study found that a compound isolated from Aloe barbadensis Miller showed strong effects on hair follicle regeneration and hair growth in warfarin-induced alopecia in rats, suggesting potential as a minoxidil alternative.
1 citations
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July 2005 in “Drugs and the pharmaceutical sciences” Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
1 citations
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September 2002 in “PubMed” This study found that using a topical 2% minoxidil solution for 6-12 months may reduce hair loss and improve hair root conditions in some women with androgenic alopecia.
1 citations
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November 1989 in “PubMed” This review discusses male-pattern baldness and notes that minoxidil has a positive but often unsatisfactory cosmetic effect; it calls for further research since specific antiandrogens for treatment are lacking.
1 citations
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November 2022 in “Journal of Cosmetic Dermatology” This review discusses the possible materials used in subcutaneous injections for alopecia, but it reports no new clinical results and highlights the need for further research.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated an herbal hair dye using the medicinal herb Eclipta alba and other natural ingredients, finding it provided satisfactory coloring effects, conditioning benefits, stability, and safety, which supports its potential as a natural alternative to synthetic hair dyes.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers formulated a herbal hair dye using Eclipta alba and evaluated it for various parameters, finding it provided satisfactory coloring, conditioning, and stability without irritation, supporting its potential as a safer alternative to synthetic dyes.
March 2026 in “Journal of Drugs in Dermatology” This study conducted a review of clinical studies from 2020 to 2025 on exosome-based dermatologic therapies, reporting improvements in skin conditions like wrinkles and scars, though with noted limitations such as small sample sizes and potential conflicts of interest.
January 2026 in “Indus journal of bioscience research.” In this study, Hibiscus rosa-sinensis extract was used to formulate and evaluate herbal cosmetic creams for their antioxidant properties, stability, and effectiveness. The formulations demonstrated strong antioxidant potential, stability under various conditions, and favorable cosmetic qualities, suggesting HRS as a beneficial ingredient in skincare products.
January 2026 in “Microorganisms” In a DNFB-induced mouse model of atopic dermatitis, this study found that both topical and oral formulations of the probiotic Bifidobacterium animalis J12 improved AD symptoms through distinct mechanisms, with topical applications reducing local inflammation and oral administration enhancing gut microbiota and reducing systemic inflammation.
January 2026 in “Open MIND” This study identified candidate compounds from a natural-product library that may interact with the PIEZO1 and MLCK pathways, potentially countering a non-androgen cause of hair follicle miniaturization, all based on computer simulations; experimental validation is necessary.
January 2026 in “Plastic & Reconstructive Surgery Global Open” This study reported that applying stem cell serum daily resulted in eyebrow hair regrowth in a patient with chronic secondary cicatricial alopecia, and prevented hair loss in another patient with acute eyebrow trauma, suggesting it as a noninvasive treatment alternative.
August 2025 in “South African Journal of Botany” This study found that among various polyherbal hair oil formulations using indigenous Bangladeshi plants, Formulation B was most effective, displaying strong antimicrobial activity and promoting hair regrowth in rabbits, surpassing the standard 2% minoxidil treatment, while also being safe for topical use.
March 2025 in “Journal of Investigative Dermatology” In this survey study, 44% of epidermolysis bullosa patients who tried cannabinoids reported effective symptom management, particularly pain relief, but concerns about cost, stigma, and accessibility remain significant. Further research is necessary to confirm these findings and optimize cannabinoid therapies for EB.
April 2024 in “Skin research and technology” This study retrospectively observed that combining microneedle minoxidil with triamcinolone acetonide showed clinical efficacy in treating alopecia areata, a condition marked by sudden patchy hair loss.
November 2023 in “Hair transplant forum international” Results are not reported in this abstract, which raises the question of whether caffeine has a stimulating effect on hair growth both in laboratory settings and live subjects.
June 2023 in “Small animal advances” This case report describes successful treatment of mange in a rabbit using topical selamectin over two weeks.
August 2022 in “Aesthetic Cosmetology and Medicine” In this study, researchers analyzed plant materials with high anti-seborrhoeic potential, reviewing current studies on plant extracts that may offer therapeutic effects against seborrhea, suggesting that natural cosmetic formulations could safely reduce seborrhea without causing side effects.
This research focused on formulating finasteride, dutasteride, and minoxidil with cyclodextrins to enhance their solubility and skin penetration for topical use, potentially reducing scalp irritation from current alcohol-based preparations.
December 2020 in “한국인그리에학회지” This study found that topical application of astringent persimmon fruit extract significantly increased hair area and length in a Black mice model, suggesting potential for promoting hair growth.