Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that radiation negatively impacts the survival and proliferation of fibroblasts on human dermis transplants, but hair follicle pores enhance cell viability even after irradiation.

This study found that an enzymatic digestion method for isolating hair follicle stem cells from scalp specimens yielded 5.3 times more epithelial cells than explant cultures, while supporting comparable cell functionality, offering a promising technique for tissue engineering and regenerative medicine.

This study found that increased ACE2 expression, prompted by mechanical stretch, promotes skin regeneration and reduces dermal thinning during tissue expansion by enhancing collagen synthesis, suggesting ACE2's potential to improve clinical outcomes in reconstructive surgery settings.

In this study, pediatric patients who underwent tissue expansion surgery reported varying quality-of-life outcomes, with a median score of +17, and most would recommend the procedure despite some negative experiences, indicating the need for further research to understand factors influencing these outcomes.

This study found that laboratory and African spiny mice have distinct spatiotemporal patterns in wound-induced hair neogenesis, with the Twist1 pathway playing a central role in epidermal-dermal interactions for hair primordia formation.

This study found that keratin scaffolds derived from human hair promoted excellent cell viability and showed minimal inflammatory response and vascular integration when tested in in vitro and in vivo settings.

This study found that injecting highly purified monocyto-angiotropin into hare skin induced new blood vessel formation and significantly accelerated hair growth at the injection site compared to control areas.

This study reviewed recent advances in regenerative technologies for aesthetic and reconstructive medicine and found that adipose-derived stem cells and platelet-rich plasma are well-established for tissue repair due to their safety and effectiveness, while emerging technologies like exosome-based therapies hold future potential.

This study found that dedifferentiated corneal epithelial cells can revert to a stem-cell-like state, aiding tissue homeostasis and repair, with this plasticity limited to the epithelial lineage and enhanced by niche-derived cytokines.

This study developed HA-gel-dex hydrogels with enhanced ECM-like properties and functionality, showing promise for 3D bioprinting, tissue repair, and as wound dressings due to improved cell interaction, cytocompatibility, antimicrobial synergy, and wound healing in mice compared to traditional ECM bio-inks.

In this study, researchers demonstrated that fibroblasts derived from human embryonic stem cells can be used to create tissue-engineered dermal substitutes, effectively repairing mouse skin wounds within 20 days, highlighting a promising method for clinical applications in skin repair.

This study analyzed gene expression profiles from multiple tissues to explore the molecular connections between obesity and immune-related processes, identifying potential links and pathways that may require further experimental validation to understand their roles in obesity fully.

This study introduces a new multiaxial bioreactor system that uniformly stretches tissue-engineered skin grafts and improves skin tissue maturation through enhanced cellular distribution and environmental monitoring.

This study found that elevated tissue RBP4 levels correlate with disease severity in alopecia areata and decrease after effective baricitinib treatment, while the rs3758539 polymorphism is linked to disease susceptibility but not to treatment response.

This study examined dermal papilla cells from hair follicles, finding that gene expression changes linked to wound healing and stem cell activity align with hair follicle regression, which could inform strategies for hair growth and skin rejuvenation.

In a study on wound healing, researchers described injectable POEGMA‐DA hydrogels as a promising non-toxic alternative to traditional wound closure methods, showing effective tissue adhesion and enhanced regeneration of skin structures in a mouse model without significant inflammation.

In this study, researchers found that mice lacking the transcription factor FOXC1 in their hair follicle stem cells had increased rounds of hair regeneration but experienced hair thinning due to impaired ability to maintain stem cell quiescence and adhesion.

This study conducted in Yemen involving 50 patients found that tissue expansion was effective for correcting scars and defects from post-burn and post-war injuries, achieving a 78% satisfaction rate with minimal complications.

This study highlights keratin biomaterials as a promising biocompatible option for wound healing and tissue regeneration but notes that further clinical studies are necessary to confirm their effectiveness.

This study constructed a 3D-printed scaffold using sodium alginate, gelatin, and alginate lyase hydrogel, which supports hair follicle regeneration in artificial skin, suggesting a promising strategy for tissue-engineered skin with functional appendages.

This study found that patients with trichodynia associated with androgenetic alopecia had significantly higher levels of substance P in both tissue and serum compared to healthy controls, suggesting a potential role for this neurotransmitter in the condition's pathogenesis.

This study developed a novel zinc-releasing hydrogel, Zn-Gel, which promoted wound healing by controlling zinc ion release and demonstrated excellent compatibility and efficacy in enhancing cell proliferation, blood vessel formation, and tissue regeneration in vitro and in vivo settings.

This study found that using overexpanded tissue expanders effectively restored the hairy scalp in 25 patients with scalp alopecia, resulting in high satisfaction and minimal complications, emphasizing the importance of careful patient selection and follow-up.

This study found that topical application of TGF-β mimic promoted enhanced wound healing and tissue regeneration in mice, suggesting its potential as a therapeutic option for improving wound healing.

This study found that toll-like receptor 9 plays a previously unrecognized role in sensing skin injury and influencing tissue repair and regeneration in adult mice by modulating γδT cell migration.

This study found that stem cell therapy before follicular unit extraction may improve hair restoration outcomes on scarred scalp tissue.

In a rat scalp expansion model, this study found that activating autophagy with rapamycin enhanced skin regeneration during tissue expansion by increasing expanded skin area, epidermis and dermis thicknesses, cell proliferation, angiogenesis, and other regenerative factors, whereas blocking autophagy reversed these effects.

This study developed a degradable and bioactive citrate-based polyurethane adhesive that achieves rapid and strong tissue adhesion, exhibiting improved bonding strength in wet environments, biocompatibility, biodegradability, and hemostatic properties, with potential to enhance wound healing by promoting angiogenesis.

This study found that nociplastic type pain is a complex and heritable trait, with significant genetic overlap with multisite chronic pain and some connection to rheumatoid arthritis and a neuropathic pain phenotype.

In this study, researchers using live mice observed that oncogenic Kras mutation disrupts hair follicle architecture by sustaining ERK signal activation, which affects stem cell behavior and tissue integrity.