In this study, researchers developed a multifunctional hydrogel for wound healing, incorporating antibacterial and antioxidant properties that demonstrated significant inflammation reduction and tissue regeneration in animal models, with high antibacterial efficacy against E. coli and S. aureus.
May 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study introduced rPanglaoDB, an R package that facilitates the integration of public scRNA-seq datasets to effectively characterize rare cell types, exemplified by generating the first unbiased transcriptome profile of fibrocytes.
August 2018 in “Chinese journal of plastic surgery” In this study, buccal mucosa grafts for urethroplasty in a rabbit model of congenital hypospadias showed good integration with minimal inflammatory response twelve weeks post-surgery.
5 citations
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April 2021 in “Journal of Mind and Medical Sciences” This review examines the interconnected roles of bone, adipose tissue, and the central nervous system in regulating energy balance, providing no new experimental results.
10 citations
,
September 2021 in “The FASEB Journal” This study found that ACKR2 plays a crucial role in reducing inflammatory skin fibrosis and promoting inflammation resolution through IFN‐β production, limiting tissue scarring.
6 citations
,
January 2020 in “International Journal of Biological Sciences” This study found that lower expression of Septin4 is significantly associated with worse outcomes in colon cancer, and its interaction with BAX in DOX treatment suggests its potential in targeted therapy.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that while niche architecture optimizes organ efficiency during hair follicle growth, it is not essential for the function of stem cell-derived tissues.
10 citations
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May 2025 in “Cell Biomaterials” This perspective highlights how advancements in single-cell sequencing and digital pathology can help understand the complex mechanisms of immune responses, fibrosis, and tissue remodeling related to medical implants, aiming to address the challenges of implant-related tissue reactions reported in this study.
49 citations
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February 2008 in “Stem Cells” This study found that after injury, the bone marrow microenvironment's increased Wnt10b expression supports hematopoietic stem cell regeneration by enhancing Wnt signaling, revealing a vital interaction during recovery.
28 citations
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September 2020 in “Pharmaceutics” This review discusses the potential of three-dimensional printed mesoporous scaffolds for drug delivery applications, particularly for bone cells and tissues, but reports no new clinical results.
7 citations
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December 2024 in “Journal of Functional Biomaterials” This review discusses the role of advanced platelet-rich fibrin (A-PRF) in oral and maxillofacial surgery, highlighting its potential benefits for healing, pain relief, and graft integration, with a need for more clinical trials to confirm long-term effects.
2 citations
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March 2025 in “Nanoenergy Advances” This review examines recent advances in bioelectronic nanogenerators for anti-cancer therapy, highlighting various transducing strategies such as photodynamic therapy and electrical stimulation, while also discussing the potential mechanisms for tissue repair and the challenges that lie ahead.
1 citations
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October 2025 This source describes wound healing as a complex biological process that requires precise regulation and coordination among various cells, cytokines, and signaling pathways to achieve tissue repair, although specific findings or results are not provided in the abstract.
May 2026 in “Scientific Reports” This study found that a bioactive borosilicate glass containing Sr and Cu ions exhibited promising mechanical strength, biocompatibility, and antibacterial activity, particularly the CuSr-1 wt.% composition, suggesting potential for use in orthopedic implants and bone tissue engineering.
June 2025 in “Materials Today Bio” In diabetic mice, this study reported that the multifunctional hydrogel CPGel achieved complete wound closure in 21 days, showing promise in improving chronic wound healing through antibacterial, antioxidative, and tissue regeneration properties.
December 2023 in “Aggregate” In this review, it is discussed how mesenchymal stem cell aggregation plays a crucial role in organ development and has potential applications in organ regeneration through tissue engineering.
5 citations
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April 2020 in “Journal of Mind and Medical Sciences” This paper presents a new device for navigational surgery utilizing the fluorescent properties of Indocyanine Green, offering enhanced intra-operative imaging capabilities by identifying tissues with an infrared CMOS camera.
June 2026 in “Clay Minerals” In this review, researchers highlighted the potential of clay minerals like kaolinite and zeolite as promising haemostatic materials, due to properties such as high water absorption and good biocompatibility, while discussing their current advances and the importance of integrating multifunctional capabilities for future wound dressings.
68 citations
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December 2014 in “Cell Biochemistry and Function” This review examines the role of nuclear hormone receptors in skin wound repair processes and reports no new clinical results, highlighting the importance of their interaction with skin cells for effective healing.
13 citations
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January 2015 in “Stem cells international” This article reviews the complex roles and therapeutic potential of Mesenchymal Stem Cells across various medical applications, emphasizing their anti-inflammatory and tissue repair functions rather than cell replacement or differentiation, and concludes that more precise measurement of their survival and effectiveness is needed.
5 citations
,
June 2024 in “Developmental Cell” In this study, activating TRPV1 nociceptors in mice skin stimulated dormant hair follicles and promoted hair growth through a mechanism involving dermal macrophages, fibroblasts, and neuropeptides, highlighting a new role for nociceptors in tissue recovery after injury.
356 citations
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March 2012 in “Trends in Plant Science” This review discusses the crosstalk between auxin and ethylene in seedling growth and development, emphasizing how ethylene modulates auxin's effects across different tissues.
14 citations
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September 2016 in “Journal of Cutaneous Pathology” This review discusses the classification and diagnosis of primary scalp alopecia, focusing on scarring and non-scarring types, and reports no new clinical results; it emphasizes simplified diagnostic pathways and tissue processing techniques.
March 2024 in “Advanced science” This study observed that a novel extracellular matrix hydrogel made from human fibroblast-derived matrix improved wound healing in animal models, showing significant effects such as hair follicle formation, reduced inflammation, enhanced pro-healing growth factor levels, and interaction with macrophages, compared to traditional collagen hydrogels.
55 citations
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February 1975 in “Journal of Cutaneous Pathology” This study observed that during the rat hair cycle, DNA synthesis in dermal cells peaks during a specific growth stage, suggesting a coordinated metabolic activity with potential implications for alopecia areata research.
20 citations
,
September 2018 in “Bioengineering & Translational Medicine” This review discusses regenerative medicine and explores the potential of molecular imaging in enhancing personalized therapies, but it reports no new research results.
2 citations
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July 2025 in “Analytical Chemistry” This study reported the development of a workflow that combines SIMS and X-ray elemental mapping techniques for multimodal imaging at the single cell level, successfully applied to visualize elements, metals, and lipids in porcine skin without loss or delocalization.
60 citations
,
September 2023 in “Science” This study found that the restoration of CD103⁺γδ T cells in humans is associated with sustained remission in inflammatory bowel disease, suggesting a conserved role for these cells in limiting disease progression.
January 2026 in “Frontiers in Drug Discovery” This study highlights that while advances in dermatology, such as biologics and JAK inhibitors, have improved treatments for conditions like atopic dermatitis and psoriasis, challenges remain, including issues with lasting efficacy and the need for more personalized therapies.
3 citations
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July 2024 in “Biomolecules” This paper explores how melatonin interacts with various magnetic fields, noting that it can enhance certain positive health effects or inhibit destructive processes, but may also exacerbate conditions like multiple sclerosis by intensifying inflammation.