2 citations
,
March 2021 in “Andrologia” In this study, mesenchymal stem cell therapy improved erectile function in a rat model of diabetes-associated erectile dysfunction, and identified 15 hub genes potentially involved in the condition's development.
1 citations
,
July 2025 in “Methods and Protocols” This study supports the use of the chicken chorioallantoic membrane as an effective pre-clinical model for burn wound research and the screening of new therapeutic agents.
1 citations
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May 2025 in “Scientific Reports” In this study, researchers analyzed skin tissues from two types of Jinlan Cashmere Goats and identified crucial non-coding RNA mechanisms potentially impacting cashmere yield, revealing significant DE lncRNAs, mRNA expressions, and pathways relevant to cashmere quality improvement.
January 2026 in “Open MIND” This upcoming review will investigate the role of hair follicle fibroblasts in androgenetic alopecia, focusing on their interactions with androgens and impact on cellular signaling and fibrosis.
This study identified a high proportion of dual TCR Treg cells in both lymphoid and non-lymphoid tissues of mice, revealing their tissue specificity, TCR repertoire characteristics, and functional phenotypes.
September 2022 in “The American journal of dermatopathology/American journal of dermatopathology” In this pilot study, researchers found no sunscreen particles in the hair follicle units of patients with frontal fibrosing alopecia, suggesting no direct link between sunscreen use and the condition.
This study suggests that skin tumor cells in tuberous sclerosis complex may promote hamartoma morphogenesis by expressing and releasing higher levels of cathepsin B.
January 2025 in “International Journal of Advancement in Life Sciences Research” This research found that crude leaf extracts of Calotropis gigantea caused significant oxidative stress and cellular damage in freshwater fish Danio rerio over 30 days, highlighting the toxicological risks of this plant despite its medicinal properties.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that infiltrating M2 macrophages promote wound-induced hair neogenesis in mice by producing growth factors that activate the wnt signaling pathway during the late phase of wound healing.
6 citations
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October 2022 in “Journal of cell science” This study re-analyzed single-cell RNAseq data from human and mouse skin, confirming and refining insights into keratin gene regulation during keratinocyte differentiation in epithelial tissues.
11 citations
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July 2022 in “Frontiers in Immunology” This study identified four immune-related signaling molecules (LGR5, PTN, JAG1, and DKK1) associated with keloid, suggesting their potential role in its pathogenesis and as targets for new treatments.
11 citations
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April 2017 in “Journal of The European Academy of Dermatology and Venereology” This study found that long non-coding RNAs are differentially expressed in androgenetic alopecia, suggesting potential roles in its development and novel targets for prevention and treatment.
August 2026 in “Frontiers in Surgery” This review article from the examined literature highlights the shift in eyebrow reconstruction techniques from traditional methods to minimally invasive and regenerative approaches, evaluating their principles, outcomes, and challenges to inform future clinical practices.
June 2023 in “Research Square (Research Square)” This study found that polycaprolactone (PCL) in facial fillers led to more cell proliferation and vascular activity than hyaluronic acid (HA) in Wistar rats, suggesting enhanced tissue regeneration effects with PCL.
1 citations
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January 2015 in “China Animal Husbandry & Veterinary Medicine” This study identified four keratin genes associated with hair follicle development that were expressed more highly in super fine wool Xinji sheep compared to fine wool sheep.
May 2026 in “BMC Medicine” This study found that ACOD1 deficiency in dermal papilla cells promotes mitochondrial dysfunction and contributes to cellular senescence in androgenetic alopecia, suggesting ACOD1 as a potential therapeutic target and 4-octyl itaconate as a promising treatment option for AGA.
54 citations
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November 2015 in “Methods in enzymology on CD-ROM/Methods in enzymology” This chapter reviews keratins in skin epithelia, including their roles in cellular function and disease, and reports no new experimental results.
April 2020 in “The Egyptian Journal of Plastic and Reconstructive Surgery” In this retrospective study of 29 patients with scalp burn alopecia, researchers utilized a simple method involving tissue expansion to reconstruct the temporal and lateral sideburn areas, resulting in satisfactory, symmetrical, and standardized aesthetic outcomes according to both objective and subjective evaluations.
688 citations
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June 2007 in “Cell Stem Cell” This study found that deleting the ATR gene in adult mice led to rapid onset of age-related traits such as hair graying and osteoporosis through reduced regenerative capacity.
1 citations
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April 2023 in “International journal of molecular sciences” In this study, AMACO was found to be non-essential for the formation or function of anchoring cords in mice, despite its presence in the structure.
April 2024 in “Human genomics” This study identified MPB susceptibility genes and potential drug candidates that may help uncover molecular mechanisms and address male-pattern baldness.
417 citations
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September 2005 in “PLoS biology” This study developed molecular signatures for dermal papilla cells and their niche, uncovering novel signaling regulators and genes linked to hair disorders, which may inform future hair development research.
160 citations
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January 2014 in “Seminars in cell & developmental biology” This review discusses the shared molecular and cellular processes in the early development stages of skin appendages like hair follicles, teeth, and mammary glands, reporting no new results.
73 citations
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August 2011 in “Stem Cell Research” This study found that human hair follicle-derived mesenchymal stem cells can differentiate into myogenic, osteogenic, adipogenic, and chondrogenic lineages, although this potential decreases over time and varies by lineage.
67 citations
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December 1990 in “The journal of cell biology/The Journal of cell biology” This study identified two evolutionarily conserved ultra-high-sulfur keratin proteins in human and sheep hair follicles, which are specifically expressed in the hair cuticle during the late stages of fiber development.
51 citations
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January 2006 in “Wound Repair and Regeneration” This study found that MRL/MpJ mouse dorsal skin wounds heal with similar scar formation and collagen deposition as C57bl/6 and Balb/c mice.
47 citations
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March 2017 in “Materials Science and Engineering: C” In this study, decellularized human amniotic membrane was found to promote wound healing and reduce scar formation in rats with full-thickness skin defects, compared to traditional clinical treatments.
44 citations
,
September 2019 in “The EMBO Journal” This study found that lymphatic vessels in mice are important for hair follicle development and organization, as their depletion blocks hair growth.
26 citations
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June 2016 in “Frontiers in Plant Science” This study describes a method to isolate and analyze young and mature type VI trichomes from wild tomato species using autofluorescence-based cell sorting.
25 citations
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January 2003 in “Plastic & Reconstructive Surgery” This study indicates that nail-matrical fibroblasts can induce hard keratin expression in non-nail-matrical keratinocytes, suggesting potential for using non-nail-matrical epidermal grafts to treat nail injuries.