19 citations
,
January 2018 in “Scientific Reports” This study provided the first proteome dataset for alopecia areata, revealing novel pathways in the disease mechanisms that may lead to new therapeutic targets.
17 citations
,
June 2018 in “Frontiers in Physiology” This study found that acellular dermal matrix scaffolds may facilitate full-thickness skin wound healing by promoting a pro-regenerative immune response through M2 macrophage polarization via the Lamtor1 pathway.
16 citations
,
December 2021 in “Frontiers in Endocrinology” This review discusses the role of sex hormones in COVID-19 severity and reports no new clinical results; the authors suggest further research for gender-based personalized treatment options.
13 citations
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June 2007 in “Journal of Dermatological Science” This study identified several genes regulated by dihydrotestosterone in an SV40T-transformed human dermal papilla cell line, which may play a role in androgen-mediated hair growth regulation.
11 citations
,
January 2013 in “Methods in molecular biology” This study describes a method for labeling and tracking hair follicle stem cells in mouse skin using a Cre/lox recombination system with tamoxifen, providing insights into stem cell behavior and contribution to tissue regeneration.
8 citations
,
November 2020 in “Nature Communications” This study demonstrates that Tp63-expressing epithelial stem cells from non-skin tissues can respond to skin morphogenetic signals and contribute to the formation of hair follicles, sebaceous glands, and epidermis.
8 citations
,
September 2016 in “Journal of Investigative Dermatology” In this study, Flii overexpression in mice enhanced fingertip regeneration and nail formation after both distal and proximal amputations, suggesting a role in digit and hair follicle regeneration possibly involving Wnt signaling.
6 citations
,
July 2023 in “Diabetology” This study in an animal model found that Rigenera® technology's use of autologous micrografts improved wound healing in diabetic rats by increasing factors like VEGF-A, IL4, and IL10 while reducing TNF-α and oxidative stress.
6 citations
,
September 2021 in “AESTHETIC OROFACIAL SCIENCE” This review discusses the cost-effectiveness and potential benefits of platelet-rich plasma for facial dermal rejuvenation but reports no new clinical results.
6 citations
,
July 2021 in “Microbial biotechnology” This study found that combining LED yellow light with an engineered strain expressing CXCL12 improved wound healing and reduced inflammation in a mouse model of scald wounds.
4 citations
,
November 2022 in “Nutrients” In a study on mice, cow placenta extract showed strong antioxidant activities and reduced collagen damage, suggesting it could help delay skin aging caused by D-galactose.
3 citations
,
December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers found that inhibiting YAP signaling in skin wounds leads to regenerative repair with active Trps1 and Wnt signaling, contrasting the typical fibrotic scarring process.
3 citations
,
June 2001 in “International Journal of Cosmetic Surgery and Aesthetic Dermatology” This article presents a rationale for using a combination of follicular units and slit grafts in hair transplanting and reports no new clinical results.
2 citations
,
April 2021 in “International Journal of Molecular Sciences” This study found that the culture conditions, not species-specific differences, determined whether sika deer dermal papilla cells adopted a 3D spheroidal or 2D monolayer growth pattern, influencing their hair-inducing ability.
2 citations
,
February 2021 in “Developmental Cell” This study reports that aging in human skin involves early photo- and inflammation-related cellular changes, and suggests restoring KLF6 and HES1 expression might reverse some of these age-associated changes.
1 citations
,
October 2022 in “Journal of Bioscience and Bioengineering” This study found that Y27632 treatment facilitated the formation of core-shell-shaped hair follicle organoids, resulting in nearly 100% efficient hair shaft sprouting in vitro.
April 2026 in “Biosensors” In this study, red-light irradiation significantly increased hair follicle numbers and ATP levels in a mouse model, highlighting low-level laser therapy's potential to enhance hair regeneration and alter the skin metabolic microenvironment.
August 2025 in “Academic International Journal of Veterinary Medicine” In this experimental study on rabbits, researchers found that while aloe vera extract did not change the visible wound healing rate, it enhanced histological recovery, promoting early re-epithelialization and minimal inflammation, indicating superior tissue regeneration compared to untreated wounds.
January 2025 in “Dialnet (Universidad de la Rioja)” In this multicenter study, adipose-derived stem cell-enriched fat grafting achieved higher satisfaction and better clinical outcomes compared to platelet-rich plasma and hyaluronic acid filler in aesthetic interventions.
January 2023 in “Biomaterials Science” This study suggests that incorporating matrisomal components into biomaterials could enhance skin wound healing in mammals that do not naturally regenerate tissues like the axolotl and Acomys.
This study found changes in the PGI2 pathway, especially in gene and protein expression, in diabetic mice, but did not observe PGI2-dependent vasomotor dysfunction.
January 2022 in “Optometric clinical practice” This case report describes a 59-year-old woman with a rare trichoepithelioma on her eyelid, emphasizing the importance for optometrists to differentiate it from basal cell carcinoma.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that manipulating both gene expression and matrix stiffness in mice can alter hair regeneration after skin wounding, highlighting key factors in regenerative biology.
April 2017 in “Journal of Investigative Dermatology” This study suggests that dermal Wnt/β-catenin activation timing is crucial for hair follicle initiation, with potential non-cell autonomous regulation of dermal condensate size.
January 2014 in “International Journal of Dermatology and Venereology” This case report describes a 42-year-old male with alopecia areata and a scalp neurofibroma, emphasizing the tumor's histopathological features and the patient's decision against surgical treatment.
January 2013 in “Revista Clínica Española” This review discusses female hyperandrogenism, detailing diagnostic criteria and treatment options without reporting new study results; it emphasizes improving health and quality of life for affected women.
January 2002 in “Academic Journal of Kunming Medical College” In this study, human-hair artificial tendon material showed good biocompatibility and variable degradation rates in rabbits, depending on treatment time, with minimal inflammatory reactions observed.
52 citations
,
February 1986 in “Journal of Histochemistry & Cytochemistry” This study found that monoclonal antibodies can identify specific immunological characteristics of hair fibrous proteins, with some antibodies reacting only with hair proteins and others showing broader activity with skin and epithelial cells.
15 citations
,
February 2009 in “Cell Stem Cell” This study found that hair germ cells, derived from bulge stem cells, respond faster to dermal papilla signals and have limited proliferation compared to bulge cells during hair regeneration.
July 2026 in “Editora Pasteur eBooks” This study assesses the potential of exosomes as a therapeutic option for androgenetic alopecia, examining their mechanisms and effectiveness. The authors conducted a systematic review of existing research to explore how these extracellular vesicles might stimulate hair growth and restore follicle function.