September 2025 in “Medicine” This study found that male patients with androgenetic alopecia exhibited signs of increased arrhythmia risk, such as higher P-wave dispersion and lower corrected QT interval on ECG, suggesting potential benefits from closer cardiac monitoring.
September 2025 in “Journal of Psychiatry Spectrum” This case report describes a rare instance of gynecomastia in a male patient undergoing mirtazapine treatment for depression, suggesting the drug as a probable cause after ruling out other factors.
January 2025 in “Indian Journal of Paediatric Dermatology” This study found no significant difference in serum Vitamin D levels between children with alopecia areata and healthy controls, nor was there any correlation between Vitamin D levels and the severity, duration, or pattern of the condition, or nail changes.
June 2024 in “British Journal of Dermatology” This study found that there is substantial variability in laboratory testing practices among dermatologists specializing in alopecia areata across the globe, indicating the need for renewed discussions around guidelines for such testing.
April 2022 in “Authorea (Authorea)” This study reports two cases where localized prostate cancer with low PSA levels was incidentally detected through CT scans performed for other medical reasons.
July 2019 in “Dermatology practical & conceptual” This report presents personal observations of alopecia areata in twins with autoimmune thyroiditis and suggests a possible link, though it does not provide new clinical results.
July 2005 in “The American Journal of Human Genetics” The AR gene is linked to male-pattern baldness, TNFSF4 to heart disease, SLC19A3 to BBGD, MCT8 to a syndrome, and segmental duplications to genetic variation.
4 citations
,
March 2025 in “Pediatric Dermatology” This review examines the clinical presentation of alopecia areata in children and compares it to adult-onset cases, noting that data on pediatric cases is scarce and often varies, with reported onset typically between ages 6 and 12.
70 citations
,
April 2020 in “Journal of Molecular Cell Biology” This review summarizes recent advances in organoid technology for generating tissue models from the three germ layers and reports no new experimental results.
22 citations
,
May 2016 in “Breast cancer research and treatment” This study reported cold thermal injuries on the scalp in four patients using cold caps to prevent chemotherapy-induced alopecia, suggesting improper application can lead to adverse events.
18 citations
,
March 2014 in “Journal of Pharmacological and Toxicological Methods” This study found that ovariectomized and finasteride-treated rats showed significant tear film deficiency and downregulation of sex steroid receptors in ocular tissues, suggesting potential models for studying dry eye disorders.
11 citations
,
October 2021 in “Orphanet journal of rare diseases” This study found that patients with RASopathies have lower serum IgA and CD8 levels compared to controls, indicating a potential risk for developing autoimmune disorders.
9 citations
,
March 2022 in “Frontiers in Endocrinology” This study found that PCOS is common among Iranian women, with phenotypes involving hyperandrogenism exhibiting worse lipid profiles and higher rates of metabolic syndrome compared to healthy women.
8 citations
,
May 2025 in “Pharmaceuticals” This article reviews 27 small-molecule drugs approved by the FDA in 2024, noting that among them, eight "first-in-class" drugs with breakthrough therapy status show distinct mechanisms and substantial efficacy improvements in various conditions like cancer and chronic diseases.
6 citations
,
December 2022 in “International Journal of Molecular Sciences” This review explores the hormonal factors related to hidradenitis suppurativa, emphasizing insulin resistance and pro-inflammatory adipokines, but reports no new clinical findings and suggests further research is needed.
5 citations
,
March 2023 in “International Journal of Trichology” This study reported a similar prevalence of metabolic syndrome in patients with alopecia areata as in healthy controls, with no statistically significant differences observed.
3 citations
,
April 2020 in “Clinical endocrinology and metabolism journal” This review discusses imaging's role in the diagnosis and management of congenital adrenal hyperplasia and reports no new clinical results; it suggests a potential presentation route via incidental radiologic findings.
3 citations
,
January 2020 in “Indian Dermatology Online Journal” In this study, significant correlations were observed between acanthosis nigricans and factors like free testosterone, DHEAS, fasting blood sugar, and BMI, as well as between hirsutism and elevated DHEAS, free testosterone, and BMI among patients with polycystic ovarian disease.
2 citations
,
October 2023 in “Biology” This review highlights cobalt's essential role in vitamin B12 metabolism and its biomedical applications but also warns of health risks from high levels and environmental contamination, discussing remediation methods like phytoremediation.
2 citations
,
July 2022 in “Indian Journal of Dermatology Venereology and Leprology” This study found that patients with premature greying of hair had significant abnormalities in cardiovascular risk markers, including elevated IL-6 levels, compared to healthy controls.
1 citations
,
June 2023 in “Cureus” In this study, researchers found that among adolescent and adult female patients with seborrheic dermatitis, 60.9% had cutaneous comorbidities like acne, while 28.3% had systemic comorbidities such as diabetes mellitus, though not all associations were statistically significant.
1 citations
,
June 2023 in “Journal of Dermatology” This study found that patients with alopecia areata had a higher prevalence of autoimmune, inflammatory, and mental health conditions compared to a matched cohort without alopecia areata.
1 citations
,
January 2018 in “Advances in cancer prevention” This review discusses the preventable nature of many cancers due to modifiable risk factors and emphasizes the importance of preventive oncology in reducing the global cancer burden; it reports no new clinical results.
In this study, nearly two-thirds of Saudi adults reported experiencing hair loss following COVID-19 infection or vaccination, with female sex and nutritional deficiencies identified as significant correlates for this condition.
April 2026 in “Frontiers in Immunology” In this study, researchers did not find any genome-wide significant genetic signals linked to comorbid chronic inflammatory disorders in patients with alopecia areata, but exploratory analysis suggested potential associations worth further study.
November 2025 in “IntechOpen eBooks” This chapter reviews the complex relationship between PCOS and sexual dysfunction, highlighting its fundamental role as a biopsychosocial manifestation rather than a secondary complication, and calls for comprehensive, patient-centered care; it reports no new clinical results.
November 2025 in “Molecules” This review examines recent advancements in green and emerging microextraction techniques, such as SPME and DLLME, for more sustainable hormone detection in biological samples, emphasizing environmentally friendly solvents and bioanalytical applications.
October 2025 in “Medicine” This case report presents a patient with idiopathic isolated ACTH deficiency and testicular germ cell tumor, with alopecia areata as an initial symptom, suggesting a potential link between these conditions.
July 2025 in “Journal of Education Health and Sport” This review found that androgenetic alopecia may be associated with increased risks of cardiovascular disease, metabolic disorders, and mental health impacts, suggesting its potential as a biomarker for systemic conditions.
July 2025 in “Bioactive Materials” This review summarizes advancements in biomedical engineering for hair follicle regeneration, highlighting strategies like cell transplantation and tissue engineering to reconstruct hair follicles, and discusses both their technical limitations and potential future innovations in regenerative medicine.