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    Glossary Thyroid Hormone Receptors

    proteins in cells that bind thyroid hormones to regulate genes

    Thyroid Hormone Receptors (THRs) are proteins found in cells that bind to thyroid hormones, which are crucial for regulating metabolism, growth, and development. When thyroid hormones attach to these receptors, they influence the expression of specific genes, thereby affecting various physiological processes. This interaction is essential for maintaining normal metabolic function and can impact conditions like alopecia if disrupted.

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    1. Thyroid receptor β: A promising target for developing novel anti-androgenetic alopecia drugs Drug discovery today · 2024
    2. Thyroid receptor agonists for the treatment of androgenetic alopecia Bioorganic & Medicinal Chemistry Letters · 2009 · 19 citations
    3. Thyroid hormone receptor β1 is expressed in the human hair follicle 2000 · 111 citations
    4. A Novel Missense Mutation Affecting the Human Hairless Thyroid Receptor Interacting Domain 2 Causes Congenital Atrichia Journal of Investigative Dermatology · 2002 · 26 citations
    5. Impaired Hair Growth and Wound Healing in Mice Lacking Thyroid Hormone Receptors PloS one · 2014 · 24 citations
    6. Thyroid Hormone Receptor Agonist Promotes Hair Growth in Mice Clinical, Cosmetic and Investigational Dermatology · 2022 · 1 citations
    7. Alopecia and Thyroid Disease Springer eBooks · 2008
    8. The <i>hairless</i> gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor Genes & Development · 2001 · 178 citations
    9. Expression of Hypothalamic–Pituitary–Thyroid Axis RelatedGenes in the Human Skin Journal of Investigative Dermatology · 2002 · 155 citations
    10. Hairless is a nuclear receptor corepressor essential for skin function Nuclear Receptor Signaling · 2009 · 30 citations
    11. Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An <i>in Silico</i> and <i>in Vitro</i> Study Environmental health perspectives · 2020 · 29 citations
    12. Expression Profiles of Reproduction- and Thyroid Hormone-Related Transcripts in the Brains of Chemically-Induced Intersex Frogs Sexual Development · 2011 · 24 citations
    13. Thyroid hormones and androgens differentially regulate gene expression in testes and ovaries of sexually mature Silurana tropicalis General and comparative endocrinology · 2018 · 13 citations
    14. Hairless: A nuclear receptor corepressor essential for skin function Advances in developmental biology · 2006
    15. Thyroid-Stimulating Hormone, a Novel, Locally Produced Modulator of Human Epidermal Functions, Is Regulated by Thyrotropin-Releasing Hormone and Thyroid Hormones Endocrinology · 2010 · 105 citations
    16. Human Female Hair Follicles Are a Direct, Nonclassical Target for Thyroid-Stimulating Hormone Journal of Investigative Dermatology · 2008 · 90 citations
    17. Exploring the “Thyroid–Skin Connection”: Concepts, Questions, and Clinical Relevance Journal of Investigative Dermatology · 2009 · 49 citations
    18. Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease Endocrine Related Cancer · 2019 · 25 citations
    19. Voice changes in reproductive disorders, thyroid disorders and diabetes: a review Endocrine connections · 2022
    20. Abstract #1182315: Biotin and thyroid function test Endocrine practice · 2022
    21. 6525 Alternating Hypothyroidism and Hyperthyroidism Complicated by Thyroid Eye Disease Journal of the Endocrine Society · 2024
    22. MON-594 Alternating Hypothyroidism and Hyperthyroidism Complicated by Thyroid Eye Disease Journal of the Endocrine Society · 2024
    23. Thyroid hormone action on skin Dermato-endocrinology · 2011 · 44 citations
    24. Thyroid hormone action on skin Current Opinion in Endocrinology, Diabetes and Obesity · 2012 · 30 citations
    25. Cell type‐specific actions of thyroid hormones in nonalcoholic steatohepatitis and liver fibrosis Liver International · 2024 · 3 citations
    26. Potential Therapeutic Uses of Thyroid Hormone Springer eBooks · 2008
    27. Vitamin D receptor-mediated control of Soggy, Wise, and Hairless gene expression in keratinocytes 2013 · 13 citations
    28. Immune-Molecular Link between Thyroid and Skin Autoimmune Diseases: A Narrative Review Journal of Clinical Medicine · 2024 · 6 citations
    29. Selective Pituitary Resistance to Thyroid Hormone: Clinical Hyperthyroidism with High TSH on Levothyroxine Administration in I-131 Ablated “Graves Disease” Open Journal of Endocrine and Metabolic Diseases · 2022 · 1 citations
    30. Molecular Genetic and Endocrine Mechanisms of Hair Growth Hormone Research in Paediatrics · 2003 · 51 citations