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    Glossary Thyroid Hormone Receptors

    proteins in cells that bind thyroid hormones to regulate genes

    Thyroid Hormone Receptors (THRs) are proteins found in cells that bind to thyroid hormones, which are crucial for regulating metabolism, growth, and development. When thyroid hormones attach to these receptors, they influence the expression of specific genes, thereby affecting various physiological processes. This interaction is essential for maintaining normal metabolic function and can impact conditions like alopecia if disrupted.

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    1. Thyroid Hormone Receptor Agonist Promotes Hair Growth in Mice Clinical, Cosmetic and Investigational Dermatology · 2022 · 1 citations
    2. The <i>hairless</i> gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor Genes & Development · 2001 · 178 citations
    3. Hairless is a nuclear receptor corepressor essential for skin function Nuclear Receptor Signaling · 2009 · 30 citations
    4. A Novel Missense Mutation Affecting the Human Hairless Thyroid Receptor Interacting Domain 2 Causes Congenital Atrichia Journal of Investigative Dermatology · 2002 · 26 citations
    5. Canine alopecia X-Like disorder Brazilian journal of veterinary pathology · 2024
    6. Epidermal Renewal after Treatment of Primary Canine Hypothyroidism using Levothyroxine Acta Scientiae Veterinariae · 2021
    7. Low Free Thyroxine (FT4) in critically ill juvenile systemic lupus erythematosus: a diagnostic approach Intisari Sains Medis · 2024
    8. Thyroidism Effect on Alopecia Patients In Pakistan International Journal of Immunology and Microbiology · 2021
    9. Incidence and haemato-biochemical alterations in dermatoses associated with hypothyroidism in dogs International Journal of Advanced Biochemistry Research · 2026
    10. Functional mapping of the mouse <i>hairless</i> gene promoter region bioRxiv (Cold Spring Harbor Laboratory) · 2018
    11. Thyroid hormone action in epidermal development and homeostasis and its implications in the pathophysiology of the skin Journal of endocrinological investigation · 2021 · 32 citations
    12. Relationship between betacoronaviruses and the endocrine system: a new key to understand the COVID-19 pandemic—A comprehensive review Journal of Endocrinological Investigation · 2021 · 23 citations
    13. Concurrent autoimmune and endocrine dysregulation in polycystic ovary syndrome Middle East Fertility Society Journal · 2025 · 1 citations
    14. Genome-wide association study of atopic and autoimmune comorbidities in alopecia areata Frontiers in Immunology · 2026
    15. Triglycerides, independent of Ferriman Gallwey Score, is a main determinant of free testosterone index in PCOS F1000Research · 2019 · 6 citations
    16. The AR/miR-221/IGF-1 pathway mediates the pathogenesis of androgenetic alopecia International Journal of Biological Sciences · 2023 · 2 citations
    17. Dermatological alterations induced by gynecological hormonal imbalances: Acne, hirsutism and alopecia Zenodo (CERN European Organization for Nuclear Research) · 2025
    18. Dermatological alterations induced by gynecological hormonal imbalances: Acne, hirsutism and alopecia Zenodo (CERN European Organization for Nuclear Research) · 2025
    19. The seasonal development dynamics of the yak hair cycle transcriptome Research Square (Research Square) · 2019 · 5 citations
    20. Prostate Specific Antigen as Predictive Factor for Androgenemia in Women Indian Journal of Forensic Medicine & Toxicology · 2022
    21. Alopecia areata difusa en paciente con enfermedad tiroidea autoinmune: presentación atípica y revisión de la literatura Ciencia Latina Revista Científica Multidisciplinar · 2026
    22. Prediction of the Development of Depression in Patients with Autoimmune Thyroiditis and Hypothyroidism Open Access Macedonian Journal of Medical Sciences · 2022 · 1 citations
    23. Genome-Wide Association Study of Fiber Diameter in Alpacas Animals · 2023 · 1 citations
    24. GLP-1 RAs and Skin Health: Exploring Dermatologic Side Effects and Therapeutic Interventions 2025
    25. Dermatological adverse reactions and therapeutic potential of semaglutide, liraglutide and tirzepatide: Analysis of UK pharmacovigilance data and literature review 2025 · 1 citations
    26. Interactions of the Vitamin D Receptor with the Corepressor Hairless Journal of Biological Chemistry · 2007 · 42 citations
    27. Autoimmune thyroid disease and human health: a systematic review of Mendelian randomization studies Frontiers in Immunology · 2025 · 4 citations
    28. Hairless and Wnt Signaling: Allies in Epithelial Stem Cell Differentiation Cell Cycle · 2006 · 74 citations
    29. Polycystic Ovarian Morphology is Associated with Hyperandrogenemia and Insulin Resistance in Women with Polycystic Ovary Syndrome (PCOS) Journal of Steroids & Hormonal Science · 2016 · 2 citations
    30. The Modulatable Stem Cell Niche: Tissue Interactions during Hair and Feather Follicle Regeneration Journal of Molecular Biology · 2015 · 66 citations