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    Glossary Thyroid Hormone Receptors

    proteins in cells that bind thyroid hormones to regulate genes

    Thyroid Hormone Receptors (THRs) are proteins found in cells that bind to thyroid hormones, which are crucial for regulating metabolism, growth, and development. When thyroid hormones attach to these receptors, they influence the expression of specific genes, thereby affecting various physiological processes. This interaction is essential for maintaining normal metabolic function and can impact conditions like alopecia if disrupted.

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    1. Thyroid hormone receptor β1 is expressed in the human hair follicle 2000 · 111 citations
    2. Selective Pituitary Resistance to Thyroid Hormone: Clinical Hyperthyroidism with High TSH on Levothyroxine Administration in I-131 Ablated “Graves Disease” Open Journal of Endocrine and Metabolic Diseases · 2022 · 1 citations
    3. Cell type‐specific actions of thyroid hormones in nonalcoholic steatohepatitis and liver fibrosis Liver International · 2024 · 3 citations
    4. Thyroid Hormone Receptor Agonist Promotes Hair Growth in Mice Clinical, Cosmetic and Investigational Dermatology · 2022 · 1 citations
    5. Ovarian sex steroid receptors and sex hormones in androgenized rats Reproduction · 2016 · 13 citations
    6. Impaired Hair Growth and Wound Healing in Mice Lacking Thyroid Hormone Receptors PloS one · 2014 · 24 citations
    7. Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation The Journal of Clinical Endocrinology & Metabolism · 2008 · 115 citations
    8. Thyroid hormones and androgens differentially regulate gene expression in testes and ovaries of sexually mature Silurana tropicalis General and comparative endocrinology · 2018 · 13 citations
    9. The <i>hairless</i> gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor Genes & Development · 2001 · 178 citations
    10. Canagliflozin alleviates progestin resistance by suppressing RARβ/CRABP2 signaling in THRB knockout endometrial cancer cells Frontiers in Pharmacology · 2025
    11. FFA Patient Profile Analysis Based on the Authors’ Observations and a Review of the Literature—An Original Survey Journal of Clinical Medicine · 2025 · 1 citations
    12. The Endocrine Function of the Skin: An Analytical Narrative Apollo medicine · 2023
    13. Endocrinology of the Aging Prostate: Current Concepts Frontiers in Endocrinology · 2021 · 21 citations
    14. Human Female Hair Follicles Are a Direct, Nonclassical Target for Thyroid-Stimulating Hormone Journal of Investigative Dermatology · 2008 · 90 citations
    15. Expression Profiles of Reproduction- and Thyroid Hormone-Related Transcripts in the Brains of Chemically-Induced Intersex Frogs Sexual Development · 2011 · 24 citations
    16. Growth Hormone and the Human Hair Follicle International journal of molecular sciences · 2021 · 14 citations
    17. Evaluating the Role of Thyroid Stimulating Hormone and Ferritin Levels with Hair Loss among Patients with COVID-19: Case-Control Study Clinical medicine and medical research · 2023
    18. Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels Recent Patents on Endocrine, Metabolic & Immune Drug Discovery · 2007 · 20 citations
    19. Hormonal Effects on Hair Follicles International journal of molecular sciences · 2020 · 102 citations
    20. Relationship between betacoronaviruses and the endocrine system: a new key to understand the COVID-19 pandemic—A comprehensive review Journal of Endocrinological Investigation · 2021 · 23 citations
    21. Endocrine controls of primary adult human stem cell biology: Thyroid hormones stimulate keratin 15 expression, apoptosis, and differentiation in human hair follicle epithelial stem cells in situ and in vitro European Journal of Cell Biology · 2010 · 42 citations
    22. The Thyroid Hormone Analogue KB2115 (Eprotirome) Prolongs Human Hair Growth (Anagen) Ex Vivo Journal of Investigative Dermatology · 2016 · 17 citations
    23. Harnessing neuroendocrine controls of keratin expression: A new therapeutic strategy for skin diseases? BioEssays · 2014 · 26 citations
    24. GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects Frontiers in Endocrinology · 2021 · 59 citations
    25. Endocrinologia e Medicina Estética Ed. X Editora Pasteur eBooks · 2026
    26. Effects of Flutamide, a pure antiandrogen, on endocrine parameters, in the adult female rat Gynecological Endocrinology · 1987 · 8 citations
    27. Vitamin D metabolism and function in the skin Molecular and cellular endocrinology · 2011 · 185 citations
    28. Effect of a transcriptional inactive or absent vitamin D receptor on beta-cell function and glucose homeostasis in mice 2016 · 13 citations
    29. Neuroendocrine Controls of Keratin Expression in Human Skin IntechOpen eBooks · 2018
    30. Game Changers: Blockbuster Small-Molecule Drugs Approved by the FDA in 2024 Pharmaceuticals · 2025 · 8 citations