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    Glossary Thyroid Hormone Receptors

    proteins in cells that bind thyroid hormones to regulate genes

    Thyroid Hormone Receptors (THRs) are proteins found in cells that bind to thyroid hormones, which are crucial for regulating metabolism, growth, and development. When thyroid hormones attach to these receptors, they influence the expression of specific genes, thereby affecting various physiological processes. This interaction is essential for maintaining normal metabolic function and can impact conditions like alopecia if disrupted.

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    1. Thyroid Hormone Receptor Agonist Promotes Hair Growth in Mice Clinical, Cosmetic and Investigational Dermatology · 2022 · 1 citations
    2. Thyroid receptor agonists for the treatment of androgenetic alopecia Bioorganic & Medicinal Chemistry Letters · 2009 · 19 citations
    3. Cell type‐specific actions of thyroid hormones in nonalcoholic steatohepatitis and liver fibrosis Liver International · 2024 · 3 citations
    4. Emerging pharmacotherapies for Androgenetic Alopecia Expert Opinion on Pharmacotherapy · 2026
    5. Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An <i>in Silico</i> and <i>in Vitro</i> Study Environmental health perspectives · 2020 · 29 citations
    6. Impaired Hair Growth and Wound Healing in Mice Lacking Thyroid Hormone Receptors PloS one · 2014 · 24 citations
    7. A 12-week treatment with the long-acting glucagon-like peptide 1 receptor agonist liraglutide leads to significant weight loss in a subset of obese women with newly diagnosed polycystic ovary syndrome Hormones · 2015 · 61 citations
    8. GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects Frontiers in Endocrinology · 2021 · 59 citations
    9. Hormone therapy in acne Indian Journal of Dermatology, Venereology and Leprology · 2013 · 24 citations
    10. Thyroid receptor β: A promising target for developing novel anti-androgenetic alopecia drugs Drug discovery today · 2024
    11. The Thyroid Hormone Analogue KB2115 (Eprotirome) Prolongs Human Hair Growth (Anagen) Ex Vivo Journal of Investigative Dermatology · 2016 · 17 citations
    12. Endocrinologia e Medicina Estética Ed. X Editora Pasteur eBooks · 2026
    13. Impact of Thyroid Dysfunction on Hair Disorders Cureus · 2023
    14. Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance Dermatologic Clinics · 2007 · 4 citations
    15. The Potential Utility of Tirzepatide for the Management of Polycystic Ovary Syndrome Journal of Clinical Medicine · 2023
    16. Women With Polycystic Ovary Syndrome: A Review of Susceptibility to Type 2 Diabetes Cureus · 2023
    17. Fadrozole and finasteride exposures modulate sex steroid- and thyroid hormone-related gene expression in Silurana (Xenopus) tropicalis early larval development General and Comparative Endocrinology · 2009 · 60 citations
    18. Benefit-Risk Assessment of GLP-1 Receptor Agonists: Implications for Dermatologists and Plastic Surgeons Dermatology and Therapy · 2025 · 1 citations
    19. Parathyroid hormone-related peptide and the hair cycle - is it the agonists or the antagonists that cause hair growth? Experimental Dermatology · 2014 · 9 citations
    20. Canagliflozin alleviates progestin resistance by suppressing RARβ/CRABP2 signaling in THRB knockout endometrial cancer cells Frontiers in Pharmacology · 2025
    21. Game Changers: Blockbuster Small-Molecule Drugs Approved by the FDA in 2024 Pharmaceuticals · 2025 · 8 citations
    22. Topical L‐thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy? Experimental Dermatology · 2020 · 9 citations
    23. The Effect of Parathyroid Hormones on Hair Follicle Physiology: Implications for Treatment of Chemotherapy-Induced Alopecia Skin Pharmacology and Physiology · 2015 · 15 citations
    24. Hormone und Haarwachstum Hautarzt · 2010 · 24 citations
    25. Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels Recent Patents on Endocrine, Metabolic & Immune Drug Discovery · 2007 · 20 citations
    26. A CLINICAL STUDY OF CUTANEOUS MANIFESTATIONS IN PATIENTS WITH THYROID DISORDERS Journal of evolution of medical and dental sciences · 2016 · 2 citations
    27. Minireview: vitamin D receptor: new assignments for an already busy receptor. - eScholarship 2006
    28. Sex Hormone-Binding Globulin (SHBG) as an Early Biomarker and Therapeutic Target in Polycystic Ovary Syndrome International Journal of Molecular Sciences · 2020 · 58 citations
    29. Deletion of Deoxyribonucleic Acid Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D Molecular Endocrinology · 2002 · 277 citations
    30. Redefining hormone resistance in prostate cancer Therapeutic Advances in Medical Oncology · 2009 · 38 citations