2 citations,
September 2023 in “International journal of molecular sciences” Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
September 2023 in “Current opinion in microbiology” Certain fungi protect skin health, but changes can allow harmful fungi to cause serious infections, needing more research for treatment and control.
105 citations,
January 2010 in “Mediators of Inflammation” Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.
1 citations,
January 2016 in “Elsevier eBooks” The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.
6 citations,
November 2021 in “Frontiers in immunology” STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.
5 citations,
July 2022 in “Orphanet journal of rare diseases” RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
January 2025 in “Frontiers in Medicine” Hair follicles are key to treating vitiligo and alopecia areata, but challenges exist.
26 citations,
June 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Regenerative therapies show promise for treating vitiligo and alopecia areata.
2 citations,
March 2005 in “Journal of the American Academy of Dermatology” Wigs are still a popular solution for hair loss to maintain a youthful look.
July 2023 in “Research Square (Research Square)” Skin's uneven surface and hair follicles affect its stress and strain but don't change its overall strength, and help prevent the skin from peeling apart.
149 citations,
September 2017 in “Pharmaceutics” Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.
39 citations,
November 2016 in “Pharmaceutics” The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.
133 citations,
July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.
26 citations,
October 2021 in “Clinical, Cosmetic and Investigational Dermatology” The secretome from mesenchymal stem cells shows promise for treating skin conditions and improving skin and hair health, but more research is needed.
November 2024 in “International Journal of Cosmetic Science” Botanical extracts can improve scalp health by reducing oxidative stress.
19 citations,
September 2020 in “Pharmaceutics” Sodium Valproate nanospanlastics could be a safe and effective treatment for Androgenic Alopecia, with fewer side effects than minoxidil.
January 2024 in “Biomaterials Research” 3D-cultured cells in HGC-coated environments improve hair growth and skin integration.
January 2022 in “Stem cell biology and regenerative medicine” New biofabrication technologies could lead to treatments for hair loss.
4 citations,
March 2013 in “InTech eBooks” Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
39 citations,
March 2022 in “Nature Protocols” Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
8 citations,
May 2021 in “Bioengineering & translational medicine” Hair growth environment recreated with challenges; stem cells make successful skin organoids.
69 citations,
June 2017 in “Experimental Biology and Medicine” Advanced human skin models improve drug development and could replace animal testing.
April 2017 in “Journal of Investigative Dermatology” Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.
1 citations,
September 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin organoids from stem cells can help study and treat skin issues but face some challenges.
January 2024 in “Journal of Tissue Engineering” A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
5 citations,
December 2020 in “Bioengineering & translational medicine” Researchers used a laser to create advanced skin models with hair-like structures.
7 citations,
July 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Human skin can be reconnected to nerves using stem cells, which may help with skin health and healing.
164 citations,
February 2010 in “Journal of Cell Science” Human dermal stem cells can become functional skin pigment cells.
36 citations,
May 2016 in “Biomaterials” Endo-HSE helps grow hair-like structures from human skin cells in the lab.
24 citations,
September 2020 in “Pharmaceutics” Lidocaine-loaded microparticles effectively relieve pain and fight bacteria in wounds.