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Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.

Micro-needling effectively improves wrinkles, scars, and hair growth, but proper technique and safety are important.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

Finasteride-loaded nanoparticles may help treat alopecia.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Caffeine and siloxanetriol alginate caffeine in emulsion form can reduce fatty cell size and number, potentially treating cellulite effectively.

Minoxidil decreases LH expression, while hydralazine has mixed effects on prolyl and lysyl hydroxylase activities.

Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.

The pandemic has pushed dermatology education and care to adopt digital solutions, which are effective and likely to continue post-pandemic.

Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.

Leptin, a hormone, is important for starting hair growth.

Low-dose UVB light improves hair growth effects of certain stem cells by increasing reactive oxygen species.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.