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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

New effective scar treatments are urgently needed due to the current options' limited success.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Telocytes might help with skin repair and regeneration.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Minoxidil promotes hair growth in male pattern baldness.

Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Peripilar signs can help diagnose androgenetic alopecia and reveal its cause.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Type 2 diabetes, bacterial scalp infections, and tight hairstyles like braids and weaves are linked to a higher risk of a scarring hair loss condition in African American women.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Excessive selenium from a supplement caused toxicity but patients recovered with care.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Some patients taking antipsychotic medications experience skin reactions, ranging from mild to severe.

Certain fungi and bacteria help orchid seeds germinate and plants grow better.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.