123 citations,
December 2015 in “Journal of Neuroendocrinology” New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
117 citations,
March 2017 in “Nature Communications” Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
103 citations,
June 2018 in “International Journal of Molecular Sciences” FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.
77 citations,
July 2012 in “Journal of Investigative Dermatology” Wnt10b overexpression can regenerate hair follicles, possibly helping treat hair loss and alopecia.
68 citations,
April 2014 in “Journal of Molecular Endocrinology” The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.
65 citations,
July 2020 in “Science Advances” Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.
40 citations,
November 2016 in “Molecules” Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.
35 citations,
February 1994 in “Fundamental and applied toxicology” High doses of finasteride cause cell growth and tumors in mice.
26 citations,
September 2018 in “Neurobiology of Disease” Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.
23 citations,
January 2015 in “Stem cells international” Coating surfaces with human hair keratin improves the growth and consistency of important stem cells for medical use.
18 citations,
September 2018 in “Experimental physiology” Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.
16 citations,
February 2010 in “Journal of the European Academy of Dermatology and Venereology” Fibrosing alopecia in a pattern distribution is a unique hair loss condition that may respond to antiandrogen therapy.
14 citations,
July 2021 in “Reviews in endocrine and metabolic disorders” SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.
12 citations,
November 2020 in “Molecules” Carvone helps treat skin issues by reducing melanin and stopping harmful cell growth.
11 citations,
June 2020 in “Dermatologic Therapy” PRP treatment improves hair density and diameter in women with androgenetic alopecia.
11 citations,
March 2020 in “Cellular Signalling” XIST RNA helps regenerate hair follicles by targeting miR-424 and activating hedgehog signaling.
8 citations,
April 2015 in “Advances in Psychosomatic Medicine” Psychotropic medications can cause skin problems but also treat some skin conditions.
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June 2015 in “The American Journal of the Medical Sciences” Finasteride helps reduce blood vessel growth in diabetic rat kidneys.
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July 2021 in “Endocrinology, diabetes & metabolism” Glioblastoma cells can make androgens, which might help the tumor grow.
4 citations,
May 2018 in “Journal of Neuro-Ophthalmology” New treatments for relapsing multiple sclerosis are more effective and convenient but have higher risks of serious side effects.
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September 2019 in “Clinical and experimental dermatology” Basal cell carcinomas may differentiate similarly to hair follicles and could be influenced by hair cycle-related treatments.
2 citations,
March 2013 in “Phytotherapy Research” Ascorbigen increases hair cell growth in a lab setting but does not prevent hair loss from chemotherapy in mice.
2 citations,
March 2005 in “Cancer biology & therapy” Bexxar treatment led to a high response rate in patients with advanced-stage, treatment-resistant follicular lymphoma.
Gender-specific analysis could improve treatment for childhood systemic lupus erythematosus.
September 2017 in “Clinical and Experimental Dermatology” The document summarized various dermatology studies and case reports.
January 2015 in “Elsevier eBooks” Nanocarriers like liposomes and cyclodextrins improve how angiotensin-(1-7) is delivered in the body.
Lupus is a complex disease that requires personalized treatment because it varies greatly between individuals.
July 2003 in “Journal of Cutaneous Medicine and Surgery” High blood pressure drugs often cause skin lupus, stopping the drug usually helps. A vaccine helps prevent genital herpes and HPV-16. More frequent light therapy clears psoriasis faster. No link was found between low iron and chronic hair loss.
July 2003 in “Journal of Cutaneous Medicine and Surgery” Blood pressure drugs can cause skin lupus, but it improves after stopping the drug. The glycoprotein D vaccine works against genital herpes in some women, and the HPV-16 vaccine reduces HPV-16 infection and related diseases. More frequent light therapy clears psoriasis faster. A cream called imiquimod effectively treats a type of skin cancer. Iron supplements don't necessarily help with chronic hair loss in women.
July 2003 in “Journal of Cutaneous Medicine and Surgery” Various skin conditions like cutaneous lupus erythematosus, psoriasis, and basal cell carcinoma can be effectively treated with antihypertensive agents, NB-UVB phototherapy, and imiquimod cream respectively. Vaccines are effective against genital herpes and HPV-16 infection. Early intervention is crucial for conditions like diabetic foot ulcers and neonatal herpes. Certain dyes can cause hand dermatitis, and there's a link between smoking/drinking and psoriasis in men. No direct link was found between low iron levels and chronic hair loss in women.