19 citations,
May 2020 in “American journal of men's health” Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.
8 citations,
February 2009 in “Current Women's Health Reviews” Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.
7 citations,
April 2012 in “Clinical investigation” Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.
6 citations,
February 2014 in “Human & experimental toxicology” Testosterone injections can cause skin darkening and thickening.
6 citations,
September 2005 in “Expert Opinion on Pharmacotherapy” Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
3 citations,
March 2019 in “Post Reproductive Health” Testosterone replacement can help menopausal women with various symptoms, but should be used carefully and is not yet officially licensed in the UK for women.
2 citations,
January 2017 in “Endocrinology” Testosterone and its metabolites have varied effects on different body systems, especially during puberty.
2 citations,
March 2004 in “Reviews in Gynaecological Practice” Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.
1 citations,
October 2022 in “Adolescent Health, Medicine and Therapeutics” Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.
1 citations,
September 2021 in “Frontiers in Endocrinology” Minoxidil can help transgender males grow facial hair before starting testosterone therapy.
1 citations,
July 2015 in “Cambridge University Press eBooks” Testosterone therapy can improve sexual function in women but long-term safety is unclear.
1 citations,
April 2006 in “Seminars in Reproductive Medicine” Androgen therapy might help some women with low libido, but it has risks and should be used carefully.
1 citations,
September 2012 in “Expert Review of Endocrinology & Metabolism” Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.
January 2024 in “Brazilian Journal of Hair Health” Testosterone therapy in transgender men can lead to hair loss, with the risk increasing over time and influenced by family history.
July 2023 in “The Journal of Clinical Endocrinology and Metabolism” Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.
November 2022 in “Journal of the Endocrine Society” A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.
May 2021 in “Journal of the Endocrine Society” A woman developed male characteristics after using unregulated hormone therapy.
December 2016 in “The Journal of Sexual Medicine” Short-acting testosterone injections in a clinic are a preferred treatment for low testosterone because they work well, are convenient, and patients stick with the treatment.
October 2007 in “Postgraduate obstetrics & gynecology” Testosterone therapy can help postmenopausal women with low sexual desire but needs more safety research and should be used with estrogen therapy.
October 2007 in “Postgraduate obstetrics & gynecology” Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.
April 2006 in “Current Opinion in Endocrinology & Diabetes” Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.
75 citations,
February 2016 in “The Journal of Sexual Medicine” Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.
26 citations,
August 2014 in “PubMed” Testosterone improves mood and thinking skills; finasteride has no effect.
11 citations,
March 2016 in “Translational Andrology and Urology” Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.
6 citations,
November 2010 in “International Journal of Andrology” New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.
May 2023 in “Journal of drugs in dermatology” Most transgender patients getting laser hair removal before gender-affirming surgery are already on hormone therapy, which might affect the hair removal process.
Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.
May 2012 in “Reactions Weekly” A man developed hair loss from testosterone treatment but improved with additional medication.
21 citations,
November 2014 in “Journal of Endocrinological Investigation” Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.
20 citations,
June 2017 in “Hormone Molecular Biology and Clinical Investigation” Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.