research Visualizing Androgen Receptor Activity in Male and Female Mice
Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
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570-600 / 1000+ resultsresearch Sex Hormones and Acne: The Role of the Skin as an Endocrine Organ
Sex hormones, especially androgens, play a key role in causing acne.
research Clinical Biochemistry of Dihydrotestosterone
Understanding how DHT works is important for diagnosing and treating hormone-related disorders.
research Hormonal Therapies for Individuals with Intersex Conditions
research Defects in Androgen Biosynthesis Causing 46,XY Disorders of Sexual Development
Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.
research Intracrine and Myotrophic Roles of 5α-Reductase and Androgens
Muscles can make their own androgens, which may help muscle growth.
research Melatonin and Fleece Growth in Australian Cashmere Goats
Melatonin implants affect the growth and pattern of cashmere goat fleece depending on the time of year they are given.
research Clinical Review of Ejaculatory Dysfunction
The review suggests new ways to classify ejaculation problems and recommends different treatments based on the type of issue.
research Testosterone in COVID-19: An Adversary Bane or Comrade Boon
Testosterone's effects on COVID-19 are unclear and need more research.
research Androgen Treatment in Adolescent Males With Hypogonadism
Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.
research Testicular Seminoma in a Transgender Woman: A Case Report
Transgender women can still get testicular cancer, so proper screening is important.
research Restoration of Spermatogenesis and Male Fertility Using an Androgen Receptor Transgene
Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.
research Role of 5 Alpha-Reductase Inhibitors in the Management of Prostate Cancer
5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.
research Tissue-Selective Regulation of Androgen-Responsive Genes
The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.
research New Insights Into Testosterone Biosynthesis: Novel Observations From HSD17B3 Deficient Mice
Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
research Phosphatase Regulator NIPP1 Restrains Chemokine-Driven Skin Inflammation
NIPP1 is important for healthy skin and could help treat skin inflammation.
research GDNF Promotes Hair Formation and Cutaneous Wound Healing by Targeting Bulge Stem Cells
GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
research Hormonal Control of Vas Deferens Fluid Volume and Aquaporin Expression in Rats
Testosterone increases fluid secretion and aquaporin expression in the vas deferens, which is important for male fertility.
research Fatty Acid Composition of Selected Organs of Gerbils Maintained on a Fat-Deficient or Fat-Supplemented Diet
Gerbils on a fat-deficient diet had altered fatty acid levels, hair loss, reduced sperm, and lower body weight.
research An Exclusive Review of Melatonin Effects on Mammalian Melanocytes and Melanoma
Melatonin may inhibit melanoma growth and has potential as a cancer therapy aid, but its effects on human skin pigmentation need more research.
research Puberty induction with recombinant gonadotropin: What impact on future fertility?
The document discusses the impact of using recombinant gonadotropins for puberty induction in individuals with congenital hypogonadotropic hypogonadism (CHH), a condition characterized by inadequate secretion of LH and FSH. Historically treated with testosterone injections, recent studies over the past 20 years highlight the benefits of recombinant gonadotropins in promoting future fertility. These treatments facilitate steroidogenesis and spermatogenesis, leading to physiological puberty, including genital maturation and increased testicular volume. However, testicular volume often remains pre-pubertal, particularly in patients with bilateral cryptorchidism, though spermatogenesis is achieved in most cases after 2 years. The study emphasizes the need for larger randomized trials to optimize treatment approaches.
research Reproductive System, Male: Biology of Spermatogenesis and Toxicology
The document explains how sperm cells are produced, the role of testosterone in this process, and how toxins can reduce sperm count and fertility.
research Male Sex Hormones in Andrology Today
Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.
research Identification of Two Additional Novel Mutations in the AR Gene Associated with Severe Forms of Androgen Insensitivity Syndrome
Two new mutations in the AR gene linked to severe androgen insensitivity were found.
research Novel Androgen Receptor Gene Variant Containing a Premature Termination Codon in a Patient with Androgen Insensitivity Syndrome
A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.
research In Vitro 5α-Reductase Inhibition by Selected Ayurvedic Herbs for Androgenic Disorders
Emblica officinalis and Eclipta alba may help treat hair loss naturally.
research Bicalutamide: A Review
Bicalutamide may help treat female pattern hair loss.
research A Decade of Neglecting Sublingual Mass: A Case Report of Epidermoid Cyst
A man had a large, rare cyst in his mouth removed after 10 years, which fixed his swallowing and breathing problems.
research ST14 Interacts With TMEFF1 and Is a Predictor of Poor Prognosis in Ovarian Cancer
High levels of ST14 and TMEFF1 proteins in ovarian cancer are linked to worse patient outcomes and may be a new treatment target.
research Testosterone: The Male Sex Hormone
More research is needed to understand how testosterone is maintained in adult males.