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Oestrogens are key for bone growth during puberty in both boys and girls.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Resveratrol helps prevent finasteride-induced damage in male rats, improving reproductive function.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.

Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.

Gene mutations can cause problems in male genital development.

Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Male pattern baldness involves smaller hair follicles, larger oil glands, and other tissue changes, but not major blood supply issues.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

New treatments for male hypogonadism are effective and should be personalized.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

New genes and pathways are important for testosterone production and male sexual development.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.

Men with Kennedy disease have less chance of hair loss.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

High doses of finasteride cause cell growth and tumors in mice.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.