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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

A woman had both Graham Little-Piccardi-Lassueur syndrome, causing hair loss, and complete androgen insensitivity syndrome, making her genetically male but physically female. This suggests androgens don't affect the hair loss condition.

A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.

Finasteride significantly reduces fertility in male rats.

Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The document concludes that various drugs for men's health issues are in development, with treatments for sexual dysfunction and prostate conditions being the most advanced.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

A man with myotonic dystrophy type 1 had 28 skin cancers, suggesting a link between the disease and skin cancer, emphasizing the need for sun protection and regular skin checks.

Saw palmetto in hair products might reduce hair loss but can cause side effects.

A certain gene variation is linked to a higher risk of polycystic ovarian syndrome in South Indian women.

Need better hair loss treatments beyond minoxidil, finasteride, and transplants.

The conclusion is that more research is needed to understand if the drug finasteride causes Post-Finasteride Syndrome or if it's due to individual genetic makeup.

SHBG binding properties are unchanged in male liver cirrhosis patients.

SMR-2 and SMR-6 are much more toxic than retinoic acid, causing severe side effects.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

Darker skin in 10-year-old girls may be an early sign of puberty.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

Chesapeake Bay retrievers' hair loss is likely a breed-specific, hereditary condition linked to abnormal steroid levels and distinct skin changes.

Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.

Intralesional triamcinolone acetonide can effectively limit the progression of GLPLS.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.