20 citations,
May 1985 in “British journal of nutrition” Dietary essential fatty acids improved skin and hair conditions and partially corrected fat composition in diabetic mice.
17 citations,
June 2012 in “European journal of medicinal chemistry” New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.
16 citations,
January 2003 in “Nuclear Receptor Signaling” Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.
15 citations,
June 2020 in “Experimental Dermatology” Hormones and genes affect hair growth and male baldness.
15 citations,
October 2012 in “International Urology and Nephrology” Low-dose finasteride may cause fertility issues, but stopping it can improve sperm quality and lead to pregnancy.
15 citations,
November 2010 in “International Journal of Dermatology” Women with AGA have higher lipid levels, increasing heart disease risk.
12 citations,
September 2003 in “Current paediatrics” Early treatment of acne is important to prevent scarring and improve appearance, using medications that can have side effects.
11 citations,
December 2018 in “Assay and Drug Development Technologies” Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
11 citations,
March 2010 in “International Journal of Andrology” Finasteride 1-mg doesn't harm sperm or pregnancy chances.
10 citations,
January 2016 in “Dermatology” People with myotonic dystrophy type 1 tend to develop basal cell carcinoma at a younger age but not more frequently than others.
10 citations,
December 2008 in “Journal of Clinical Neuromuscular Disease” Finasteride can cause muscle pain and high creatine kinase levels, but stopping the medication may resolve symptoms.
9 citations,
February 2020 in “International Journal of Endocrinology” Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.
8 citations,
July 2014 in “General and Comparative Endocrinology” Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
8 citations,
February 2005 in “Veterinary dermatology” Chesapeake Bay retrievers' hair loss is likely a breed-specific, hereditary condition linked to abnormal steroid levels and distinct skin changes.
8 citations,
January 2003 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Women with myotonic dystrophy might get diseases related to male hormones because their body tissues are extra sensitive to these hormones.
7 citations,
January 1994 in “Annual Reports in Medicinal Chemistry” Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
6 citations,
August 2020 in “JCRPE” A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.
6 citations,
May 2016 in “Urolithiasis” Balding and low testosterone increase risk of urinary stones.
6 citations,
January 1996 in “Endocrine-related Cancer” Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.
5 citations,
April 2014 in “The American Journal of Dermatopathology” Foreign-body granuloma may be a marker for late-stage Lichen Planopilaris and should be considered in diagnosis.
5 citations,
June 2008 in “Acta Cirurgica Brasileira” Finasteride causes sperm production decrease in Mesocricetus auratus.
4 citations,
January 2019 in “Obstetrics & gynecology science” A PET-CT scan successfully located a hard-to-find Leydig cell tumor in a woman with hormonal symptoms.
3 citations,
March 2018 in “Pediatric Dermatology” Two children grew extra hair from taking omeprazole, which went away after they stopped the medication.
3 citations,
February 2017 in “Archives of Medical Science” Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.
3 citations,
January 1994 in “Toxicological Sciences” Finasteride causes abnormal growth in male mice cells at high doses.
3 citations,
July 1990 in “Acta dermato-venereologica” A man's baldness improved possibly due to a medication that blocks male hormones.
2 citations,
November 2022 in “Acta crystallographica. Section B, Structural science, crystal engineering and materials./Acta crystallographica. Section B, Structural science, crystal engineering and materials” A new platinum complex was made and studied, which might help fight cancer better.
2 citations,
July 2019 in “Journal of psychology & clinical psychiatry” Zinc helps reduce the severity of depression.
2 citations,
January 2015 in “Journal of cosmetology & trichology” Need better hair loss treatments beyond minoxidil, finasteride, and transplants.
1 citations,
February 2022 in “Online journal of biological sciences” The document does not determine if adults with aphallia are fertile.